Evidence map›Paper›PMID 21736762›Full record

Trial reportBMC nephrology2011

Protocol of a randomized controlled trial of culturally sensitive interventions to improve African Americans' and non-African Americans' early, shared, and informed consideration of live kidney transplantation: the Talking About Live Kidney Donation (TALK) Study.

L Ebony Boulware, Felicia Hill-Briggs, Edward S Kraus, J Keith Melancon, Raquel McGuire, Bobbie Bonhage, Mikiko Senga, Patti Ephraim, Kira E Evans, Brenda Falcone and 3 more

2 registry-linked trialsOpen access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in BMC nephrology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00932334 nacompletednot on this map

Culturally Sensitive Behavioral Interventions to Enhance Living Kidney Donation / Living Kidney Transplantation

TypeinterventionalSponsorJohns Hopkins UniversityRan2009 to 2011Enrolled145ConditionsChronic Kidney DiseaseArmsTALK PLUS, TALK Standard, Usual Care
NCT03046732 nacompletednot on this mapstarted 2016, after this paper: background citation

Reducing Barriers in Access to Kidney Transplantation: Implementing the "Explore Transplant" Education Program to Increase Patient Knowledge and to Facilitate Informed Decision Making- A Pilot Study

TypeinterventionalSponsorUniversity Health Network, TorontoRan2016 to 2017Enrolled227ConditionsEndstage Kidney DiseaseArmsImplementing "Explore Transplant" Education
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Interventions for increasing solid organ donor registration.The Cochrane database of systematic reviews · 2021
    Pooled it
  3. The Multidisciplinary Support To Access living donor Kidney Transplant (MuST AKT) intervention: A Pilot Randomized Controlled Trial.Transplant international : official journal of the European Society for Organ Transplantation · 2026
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  5. Transplant social worker and donor financial assistance to increase living donor kidney transplants among African Americans: The TALKS Study, a randomized comparative effectiveness trial.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

L Ebony BoulwareDivision of General Internal Medicine, Department of Medicine, Johns Hopkins School of Medicine, 2024 E, Monument Street, Baltimore, MD 21205, USA. lboulwa@jhmi.edu
Felicia Hill-Briggs
Edward S Kraus
J Keith Melancon
Raquel McGuire
Bobbie Bonhage
Mikiko Senga
Patti Ephraim
Kira E Evans
Brenda Falcone
Misty U Troll
Nicole Depasquale
Neil R Powe
Johns Hopkins University · USNational Kidney Foundation · USJohns Hopkins Medicine · USGeorgetown University · USUniversity of California, San Francisco · US

Funding

Problem Solving &CVD Risk Management in Diabetic BlacksK01HL076644 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI HILL-BRIGGS, FELICIA · 2004 to 2008
$761k
Clinical and Behavioral Determinants of CKD DisparitiesK23DK070757 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI BOULWARE, LEIGH E · 2006 to 2010
$724k
NHLBI NIH HHS K01HL076644NIDDK NIH HHS K23DK070757PHS HHS K240502643PHS HHS R39OT07537
6 · The paper itself

Abstract

backgroundLive kidney transplantation (LKT) is underutilized, particularly among ethnic/racial minorities. The effectiveness of culturally sensitive educational and behavioral interventions to encourage patients' early, shared (with family and health care providers) and informed consideration of LKT and ameliorate disparities in consideration of LKT is unknown. METHODS/

designWe report the protocol of the Talking About Live Kidney Donation (TALK) Study, a two-phase study utilizing qualitative and quantitative research methods to design and test culturally sensitive interventions to improve patients' shared and informed consideration of LKT. Study Phase 1 involved the evidence-based development of culturally sensitive written and audiovisual educational materials as well as a social worker intervention to encourage patients' engagement in shared and informed consideration of LKT. In Study Phase 2, we are currently conducting a randomized controlled trial in which participants with progressing chronic kidney disease receive: 1) usual care by their nephrologists, 2) usual care plus the educational materials, or 3) usual care plus the educational materials and the social worker intervention. The primary outcome of the randomized controlled trial will include patients' self-reported rates of consideration of LKT (including family discussions of LKT, patient-physician discussions of LKT, and identification of an LKT donor). We will also assess differences in rates of consideration of LKT among African Americans and non-African Americans. DISCUSSION: The TALK Study rigorously developed and is currently testing the effectiveness of culturally sensitive interventions to improve patients' and families' consideration of LKT. Results from TALK will provide needed evidence on ways to enhance consideration of this optimal treatment for patients with end stage renal disease.

trial registrationClinicalTrials.gov number, NCT00932334.

Indexed as

Cross-Cultural ComparisonInformed ConsentLiving DonorsBlack or African AmericanClinical ProtocolsFemaleFollow-Up StudiesHealth Knowledge, Attitudes, PracticeHumansKidney TransplantationMalePatient Education as Topic

Identifiers

PMID21736762
PMCPMC3150247
OpenAlexW2057374254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.