ArticleBMC genetics2011
A genetic linkage map and comparative mapping of the prairie vole (Microtus ochrogaster) genome.
Article in BMC genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 19 citations in OpenAlex.
- A Demographic History of a Prairie Vole (Microtus ochrogaster) Breeding Colony (2004-2020).Journal of the American Association for Laboratory Animal Science : JAALAS · 2026Article
- Single-library chromosome-scale diploid assemblies of vole genomes resolve a species-specific duplication implicated in pair bonding.bioRxiv : the preprint server for biology · 2026Article
- A Demographic History of a Prairie Vole (bioRxiv : the preprint server for biology · 2026Article
- Natural variation in oxytocin receptor signaling causes widespread changes in brain transcription: a link to the natural killer gene complex.bioRxiv : the preprint server for biology · 2023Article
- A Neuroscientist's Guide to the Vole.Current protocols · 2021Article
- Glacial cycles drive rapid divergence of cryptic field vole species.Ecology and evolution · 2019Article
- Fatherhood alters gene expression within the MPOA.Environmental epigenetics · 2018Article
- Article
- Insight into genomic changes accompanying divergence: genetic linkage maps and synteny of Lucania goodei and L. parva reveal a Robertsonian fusion.G3 (Bethesda, Md.) · 2014Article
- A genetic map of Peromyscus with chromosomal assignment of linkage groups (a Peromyscus genetic map).Mammalian genome : official journal of the International Mammalian Genome Society · 2014Article
- Identification of variables contributing to superovulation efficiency for production of transgenic prairie voles (Microtus ochrogaster).Reproductive biology and endocrinology : RB&E · 2012Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe prairie vole (Microtus ochrogaster) is an emerging rodent model for investigating the genetics, evolution and molecular mechanisms of social behavior. Though a karyotype for the prairie vole has been reported and low-resolution comparative cytogenetic analyses have been done in this species, other basic genetic resources for this species, such as a genetic linkage map, are lacking.
resultsHere we report the construction of a genome-wide linkage map of the prairie vole. The linkage map consists of 406 markers that are spaced on average every 7 Mb and span an estimated ~90% of the genome. The sex average length of the linkage map is 1707 cM, which, like other Muroid rodent linkage maps, is on the lower end of the length distribution of linkage maps reported to date for placental mammals. Linkage groups were assigned to 19 out of the 26 prairie vole autosomes as well as the X chromosome. Comparative analyses of the prairie vole linkage map based on the location of 387 Type I markers identified 61 large blocks of synteny with the mouse genome. In addition, the results of the comparative analyses revealed a potential elevated rate of inversions in the prairie vole lineage compared to the laboratory mouse and rat.
conclusionsA genetic linkage map of the prairie vole has been constructed and represents the fourth genome-wide high-resolution linkage map reported for Muroid rodents and the first for a member of the Arvicolinae sub-family. This resource will advance studies designed to dissect the genetic basis of a variety of social behaviors and other traits in the prairie vole as well as our understanding of genome evolution in the genus Microtus.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.