Evidence map›Paper›PMID 21736720›Full record

Trial reportTrials2011

Stepped care treatment for depression and anxiety in primary care. a randomized controlled trial.

Wike Seekles, Annemieke van Straten, Aartjan Beekman, Harm van Marwijk, Pim Cuijpers

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Utility scores for different health states related to depression: individual participant data analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2017
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  5. Matching depression management to severity prognosis in primary care: results of the Target-D randomised controlled trial.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021
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  8. PsyScan e-tool to support diagnosis and management of psychological problems in general practice: a randomised controlled trial.The British journal of general practice : the journal of the Royal College of General Practitioners · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wike SeeklesDepartment of Clinical Psychology, VU University, Amsterdam, The Netherlands. wm.seekles@psy.vu.nl
Annemieke van Straten
Aartjan Beekman
Harm van Marwijk
Pim Cuijpers

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDepressive and anxiety disorders are common in general practice but not always treated adequately. Introducing stepped care might improve this. In this randomized trial we examined the effectiveness of such a stepped care model.

methodsThe study population consisted of primary care attendees aged 18-65 years with minor or major DSM-IV depressive and/or anxiety disorders, recruited through screening. We randomized 120 patients to either stepped care or care as usual. The stepped care program consisted of (1) watchful waiting, (2) guided self-help, (3) short face-to-face problem solving treatment and (4) pharmacotherapy and/or specialized mental health care. Patients were assessed at baseline and after 8, 16 and 24 weeks.

resultsSymptoms of depression and anxiety decreased significantly over time for both groups. However, there was no statistically significant difference between the two groups (IDS: P = 0.35 and HADS: P = 0.64). The largest, but not significant, effect (d = -0.21) was found for anxiety on T3. In both groups approximately 48% of the patients were recovered from their DSM-IV diagnosis at the final 6 months assessment.

conclusionsIn summary we could not demonstrate that stepped care for depression and anxiety in general practice was more effective than care as usual. Possible reasons are discussed.

trial registrationCurrent Controlled Trails: ISRCTN17831610.

Indexed as

Mental Health ServicesPrimary Health CareAdolescentAdultAgedAnti-Anxiety AgentsAntidepressive AgentsAnxiety DisordersCombined Modality TherapyFemaleHealth Services ResearchHumansMajor Depressive DisorderMaleMiddle AgedNetherlandsAnti-Anxiety AgentsAntidepressive Agents

Identifiers

PMID21736720
PMCPMC3152524

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.