Evidence map›Paper›PMID 21734144›Full record

ArticleThe American journal of tropical medicine and hygiene2011

Insect-specific flaviviruses from Culex mosquitoes in Colorado, with evidence of vertical transmission.

Bethany G Bolling, Lars Eisen, Chester G Moore, Carol D Blair

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 1 pooled it
9.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 1 synthesis or guideline pooled it, 128 citations in OpenAlex.

  1. Pooled it
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  7. Article
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  12. Intrinsic factors driving mosquito vector competence and viral evolution: a review.Frontiers in cellular and infection microbiology · 2023
    Review
  13. Article
  14. Biology and Transmission Dynamics of Aedes flavivirus.Journal of medical entomology · 2022
    Article
  15. Transcriptome Analysis of anInternational journal of molecular sciences · 2022
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Bethany G BollingArthropod-Borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado 80521, USA. bbolling@cdc.gov
Lars Eisen
Chester G Moore
Carol D Blair
Colorado State University · US

Funding

U.S. Based Collaboration in Emerging Viral and Prion Diseases-26625489N01AI025489 · NIAID · University of Texas Medical Branch · 2004 to 2004
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NIAID NIH HHS N01 AI025489NIAID NIH HHS N01-AI-25489
6 · The paper itself

Abstract

Mosquitoes were collected in Colorado during 2006 and 2007 to examine spatial and seasonal patterns of risk for exposure to Culex vectors and West Nile virus. We used universal flavivirus primers to test pools of Culex mosquitoes for viral RNA. This led to the detection and subsequent isolation of two insect-specific flaviviruses: Culex flavivirus (CxFV), which was first described from Japan, and a novel insect flavivirus, designated Calbertado virus (CLBOV), which has also been detected in California and Canada. We recorded both viruses in Cx. tarsalis and Cx. pipiens from Colorado. Furthermore, quantitative reverse transcription polymerase chain reaction (RT-PCR) revealed the presence of CxFV RNA in Cx. pipiens eggs and larvae from a laboratory colony established in 2005 and naturally infected with CxFV, suggesting vertical transmission as a means of viral maintenance in natural Culex populations. Finally, we present phylogenetic analyses of the relationships between insect-specific flaviviruses and other selected flaviviruses.

Indexed as

AnimalsColoradoCulexFlavivirusFluorescent Antibody Technique, IndirectPhylogenyReverse Transcriptase Polymerase Chain ReactionSeasons

Identifiers

PMID21734144
PMCPMC3122363
OpenAlexW2111519681

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.