ArticleThe American journal of tropical medicine and hygiene2011
Increasing incidence of Ehrlichia chaffeensis and Anaplasma phagocytophilum in the United States, 2000-2007.
Article in The American journal of tropical medicine and hygiene, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
86 citing papers in PubMed, 2 syntheses or guidelines pooled it, 212 citations in OpenAlex.
- Global prevalence of Borrelia burgdorferi and Anaplasma phagocytophilum coinfection in wild and domesticated animals: A systematic review and meta-analysis.Journal of global health · 2024Pooled it
- Human granulocytotropic anaplasmosis-A systematic review and analysis of the literature.PLoS neglected tropical diseases · 2024Pooled it
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- Retrospective Multicenter Study of Human Granulocytic Anaplasmosis, France, 2012-2024.Emerging infectious diseases · 2025Article
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- Review of Molecular Tools Used in Diagnosis ofAnimals : an open access journal from MDPI · 2025Review
- Cytokine pattern during asymptomatic Anaplasma spp. infections and effect of co-infections by malaria and helminths in schoolchildren of Franceville, southeastern Gabon.Parasites & vectors · 2025Article
- Article
- Molecular Detection ofAnimals : an open access journal from MDPI · 2024Article
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- Human risk to tick encounters in the southeastern United States estimated with spatial distribution modeling.PLoS neglected tropical diseases · 2024Article
- Molecular Detection of Tick-Borne Pathogens in Kumasi: With a First Report of Zoonotic Pathogens in Abattoir Workers.BioMed research international · 2024Article
- Zoonotic Bacterial Infections Triggering Cytokine Storm Syndrome.Advances in experimental medicine and biology · 2024Review
- Etiologies of Zoonotic Tropical Febrile Illnesses That Are Not Part of the Notifiable Diseases in Colombia.Microorganisms · 2023Review
- Complete Remission in Paralytic Late Tick-Borne Neurological Disease Comprising Mixed Involvement ofAntibiotics (Basel, Switzerland) · 2023Article
- Review
- Anaplasmosis in Pennsylvania: Clinical Features, Diagnosis, and Outcomes of Patients Diagnosed WithOpen forum infectious diseases · 2023Article
- Ticks and Tick-Borne Pathogens in Recreational Greenspaces in North Central Florida, USA.Microorganisms · 2023Article
- Tularemia cases increase in the USA from 2011 through 2019.Current research in parasitology & vector-borne diseases · 2023Article
- Article
26 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ehrlichia chaffeensis causes human monocytic ehrlichiosis, and Anaplasma phagocytophilum causes human granulocytic anaplasmosis. These related tick-borne rickettsial organisms can cause severe and fatal illness. During 2000-2007, the reported incidence rate of E. chaffeensis increased from 0.80 to 3.0 cases/million persons/year. The case-fatality rate was 1.9%, and the hospitalization rate was 49%. During 2000-2007, the reported incidence of A. phagocytophilum increased from 1.4 to 3.0 cases/million persons/year. The case-fatality rate was 0.6%, and the hospitalization rate was 36%. Rates among female patients were lower than among male patients for ehrlichiosis (rate ratio = 0.68) and anaplasmosis (rate ratio = 0.70). Most (80%) ehrlichiosis and anaplasmosis cases met only a probable case definition, although, use of a polymerase chain reaction to confirm infections increased during 2000-2007. Heightened reporting of these diseases will likely continue with improving recognition, changing surveillance practices, and appropriate application of diagnostic assays.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.