Evidence map›Paper›PMID 21734133›Full record

ArticleThe American journal of tropical medicine and hygiene2011

Etiology of suspected pneumonia in adults admitted to a high-dependency unit in Blantyre, Malawi.

Thomas K Hartung, Daniel Chimbayo, Joep J G van Oosterhout, Tarsizio Chikaonda, Gerard J J van Doornum, Eric C J Claas, Willem J G Melchers, Malcolm E Molyneux, Ed E Zijlstra

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 4 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Etiology and Risk Factors for Mortality in an Adult Community-acquired Pneumonia Cohort in Malawi.American journal of respiratory and critical care medicine · 2019
    Observational
  10. Article
  11. Article
  12. Article
  13. Development of a clinical prediction rule to diagnoseSouthern African journal of HIV medicine · 2018
    Article
  14. Article
  15. Article
  16. Review
  17. Review
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  19. Article
  20. Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Thomas K HartungDepartment of Medicine, College of Medicine, University of Malawi, Blantyre, Malawi; Department of Respiratory Medicine, Victoria Hospital, Kirkcaldy, United Kingdom. thomas.hartung@nhs.net [corrected]
Daniel Chimbayo
Joep J G van Oosterhout
Tarsizio Chikaonda
Gerard J J van Doornum
Eric C J Claas
Willem J G Melchers
Malcolm E Molyneux
Ed E Zijlstra
University of Malawi · MWVictoria Hospital · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

The microbiologic etiology of severe pneumonia in hospitalized patients is rarely known in sub-Saharan Africa. Through a comprehensive diagnostic work-up, we aimed to identify the causative agent in severely ill patients with a clinical picture of pneumonia admitted to a high-dependency unit. A final diagnosis was made and categorized as confirmed or probable by using predefined criteria. Fifty-one patients were recruited (45% females), with a mean age of 35 years (range = 17-88 years), of whom 11(22%) died. Forty-eight (94%) of the patients were seropositive for human immunodeficiency virus; 14 (29%) of these patients were receiving antiretroviral treatment. Final diagnoses were bacterial pneumonia (29%), Pneumocystis jirovecii pneumonia (27%), pulmonary tuberculosis (22%), and pulmonary Kaposi's sarcoma (16%); 39 (77%) of these cases were confirmed cases. Fifteen (29%) patients had multiple isolates. At least 3 of 11 viral-positive polymerase chain reaction (PCR) results of bronchoalveolar lavage fluid were attributed clinical relevance. No atypical bacterial organisms were found.

Indexed as

HospitalizationAdolescentAdultAgedAged, 80 and overAIDS-Related Opportunistic InfectionsBronchoalveolar Lavage FluidBronchoscopyCase ManagementFemaleHumansMalawiMaleMiddle AgedPneumoniaProspective Studies

Identifiers

PMID21734133
PMCPMC3122352
OpenAlexW2119398481

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.