Evidence map›Paper›PMID 21734118›Full record

ArticleThe American journal of tropical medicine and hygiene2011

Intermittent preventive treatment with sulfadoxine-pyrimethamine against malaria and anemia in pregnant women.

Nana O Wilson, Fatou K Ceesay, Samuel A Obed, Andrew A Adjei, Richard K Gyasi, Patricia Rodney, Yassa Ndjakani, Winston A Anderson, Naomi W Lucchi, Jonathan K Stiles

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 59 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Nana O WilsonDepartment of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, Georgia 30310, USA. nwilson@msm.edu
Fatou K Ceesay
Samuel A Obed
Andrew A Adjei
Richard K Gyasi
Patricia Rodney
Yassa Ndjakani
Winston A Anderson
Naomi W Lucchi
Jonathan K Stiles
Morehouse School of Medicine · US

Funding

Morehouse School of Medicine Center of Excellence Research Endowment ProgramS21MD000101 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI MONTGOMERY-RICE, VALERIE C. · 2001 to 2015
$74.3M
TRANSCRIPTION FACTORS AND PROSTATE CANCERG12RR003034 · NCRR · MOREHOUSE SCHOOL OF MEDICINE · PI ZHAO, XUEYING · 1986 to 2011
$32.4M
Vascular Cell Apoptosis: Mediator Role of Transforming Growth Factor-beta-1S06GM008248 · NIGMS · MOREHOUSE SCHOOL OF MEDICINE · PI HARRIS-HOOKER, SANDRA · 1989 to 2009
$19.8M
TISSUE CULTURE MODEL FOR RETINITIS PIGMENTOSA--A MOLECULAR APPROACHR25GM058268 · NIGMS · MOREHOUSE SCHOOL OF MEDICINE · PI HARRIS-HOOKER, SANDRA, STILES, JONATHAN K. · 1998 to 2023
$16.5M
Renewal Application for Clinical Research Education and Career Development (CRECDR25RR017694 · NCRR · MOREHOUSE SCHOOL OF MEDICINE · PI OFILI, ELIZABETH O. · 2002 to 2011
$5.5M
Cerebral Malaria Neurological Disorders in IndiaR21TW006804 · FIC · MOREHOUSE SCHOOL OF MEDICINE · PI STILES, JONATHAN K. · 2003 to 2005
$355k
FIC NIH HHS R21 TW006804FIC NIH HHS R21TW006804-01NCRR NIH HHS G12 RR003034NCRR NIH HHS R25 RR017694NCRR NIH HHS RR03034NIGMS NIH HHS R25 GM058268NIGMS NIH HHS S06 GM008248NIGMS NIH HHS SO6GM08248NIMHD NIH HHS S21 MD000101
6 · The paper itself

Abstract

The effectiveness of intermittent preventive treatment during pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) against malaria and anemia is unclear because of the spread of SP-resistant Plasmodium falciparum. This study evaluates the effectiveness of IPTp-SP among pregnant women attending the antenatal clinic at Korle-Bu Teaching Hospital in Accra, Ghana. A cross-sectional study comparing malaria and anemia prevalence among pregnant women using IPTp-SP with non-IPTp-SP users was conducted during June-August 2009. A total of 363 pregnant women (202 of IPTp users and 161 non-IPTp users) were recruited. A total of 15.3% of IPTp users had malaria compared with 44.7% of non-IPTp users (P < 0.001). A total of 58.4% of non-IPTp users were anemic compared with 22.8% of IPTp users (P < 0.001). When we controlled for other variables, the difference in the prevalence of malaria (odds ratio = 0.18, 95% confidence interval = 0.08-0.37) and anemia (odds ratio = 0.20, 95% confidence interval = 0.12-0.34) remained significant. The recommended IPTp-SP regimen is useful in preventing malaria and anemia among pregnant women in Ghana.

Indexed as

AdolescentAdultAnemiaAntimalarialsDrug CombinationsFemaleHumansMalariaPregnancyPregnancy Complications, ParasiticPyrimethamineSulfadoxineSurveys and QuestionnairesYoung AdultAntimalarialsDrug Combinationsfanasil, pyrimethamine drug combinationPyrimethamineSulfadoxine

Identifiers

PMID21734118
PMCPMC3122337
OpenAlexW2137587975

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.