Conserved role of Ras-GEFs in promoting aging: from yeast to mice.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

1. Yeast Chronological Lifespan: Longevity Regulatory Genes and Mechanisms.Cells · 2022
   Review
2. Insights into the Conserved Regulatory Mechanisms of Human and Yeast Aging.Biomolecules · 2020
   Review
3. Ras signaling in aging and metabolic regulation.Nutrition and healthy aging · 2017
   Review
4. The Genomes of Three Uneven Siblings: Footprints of the Lifestyles of Three Trichoderma Species.Microbiology and molecular biology reviews : MMBR · 2016
   Review
5. The Ras-Erk-ETS-Signaling Pathway Is a Drug Target for Longevity.Cell · 2015
   Article
6. Integromics network meta-analysis on cardiac aging offers robust multi-layer modular signatures and reveals micronome synergism.BMC genomics · 2015
   Article
7. Immunosuppressants in cancer prevention and therapy.Oncoimmunology · 2013
   Review
8. Recent progress in genetics of aging, senescence and longevity: focusing on cancer-related genes.Oncotarget · 2012
   Review
9. Controversial aspects of oncogene-induced senescence.Cell cycle (Georgetown, Tex.) · 2012
   Review
10. Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response.Oncotarget · 2012
    Review
11. Apple can act as anti-aging on yeast cells.Oxidative medicine and cellular longevity · 2012
    Article
12. Growth culture conditions and nutrient signaling modulating yeast chronological longevity.Oxidative medicine and cellular longevity · 2012
    Review
13. Yeast-like chronological senescence in mammalian cells: phenomenon, mechanism and pharmacological suppression.Aging · 2011
    Article

Corrections and comments

• Comment on
  RasGrf1 deficiency delays aging in mice.2011

Authors and funding

2 authors at 2 institutions in 2 countries.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as