Evidence map›Paper›PMID 21732423›Full record

ReviewGlia2011

The glia of Caenorhabditis elegans.

Grigorios Oikonomou, Shai Shaham

Abstract readReview
In one paragraph

Review in Glia, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 143 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Dietary mycotoxin toxicity inAdvances in neurotoxicology · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Evolution of Oligodendroglia and Myelin.Advances in neurobiology · 2025
    Review
  14. Dendrite glia interactions: lessons from theFrontiers in cell and developmental biology · 2025
    Review
  15. Glia Development and Function in the NematodeCold Spring Harbor perspectives in biology · 2024
    Review
  16. Glial expression of a steroidogenic enzyme underlies natural variation in hitchhiking behavior.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  17. Article
  18. Review
  19. Article
  20. Review

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Grigorios OikonomouLaboratory of Developmental Genetics, The Rockefeller University, New York, New York 10065, USA.
Shai Shaham
Rockefeller University · US

Funding

Glial control of sensory neuron functionR01NS064273 · NINDS · ROCKEFELLER UNIVERSITY · PI SHAHAM, SHAI · 2008 to 2017
$3.7M
Glial control of neuronal receptive ending morphologyR01NS073121 · NINDS · ROCKEFELLER UNIVERSITY · PI SHAHAM, SHAI · 2010 to 2014
$2.1M
Lumen formation during tubulogenesis in C. elegansR01HD052677 · NICHD · ROCKEFELLER UNIVERSITY · PI SHAHAM, SHAI · 2009 to 2010
$845k
NICHD NIH HHS R01 HD052677NICHD NIH HHS R01HD052677NINDS NIH HHS R01 NS064273NINDS NIH HHS R01NS064273NINDS NIH HHS R01 NS073121NINDS NIH HHS R01NS073121
6 · The paper itself

Abstract

Glia have been, in many ways, the proverbial elephant in the room. Although glia are as numerous as neurons in vertebrate nervous systems, technical and other concerns had left research on these cells languishing, whereas research on neurons marched on. Importantly, model systems to study glia had lagged considerably behind. A concerted effort in recent years to develop the canonical invertebrate model animals, Drosophila melanogaster and Caenorhabditis elegans, as settings to understand glial roles in nervous system development and function has begun to bear fruit. In this review, we summarize our current understanding of glia and their roles in the nervous system of the nematode C. elegans. The recent studies we describe highlight the similarities and differences between C. elegans and vertebrate glia, and focus on novel insights that are likely to have general relevance to all nervous systems.

Indexed as

AnimalsCaenorhabditis elegansHumansMyelin SheathNeurogliaNeuromuscular JunctionNeuronal PlasticityPhagocytosisSensory Receptor CellsSynapses

Identifiers

PMID21732423
PMCPMC3117073
OpenAlexW2119517361

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.