SynthesisKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2012
Does computer-assisted surgery improve postoperative leg alignment and implant positioning following total knee arthroplasty? A meta-analysis of randomized controlled trials?
Synthesis in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
112 citing papers in PubMed, 7 syntheses or guidelines pooled it, 239 citations in OpenAlex.
- Patient-specific instrumentation improved axial alignment of the femoral component, operative time and perioperative blood loss after total knee arthroplasty.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2019Pooled it
- Current state of computer navigation and robotics in unicompartmental and total knee arthroplasty: a systematic review with meta-analysis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2016Pooled it
- No difference in mechanical alignment and femoral component placement between patient-specific instrumentation and conventional instrumentation in TKA.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2015Pooled it
- A meta-analysis of minimally invasive and conventional medial parapatella approaches for primary total knee arthroplasty.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2015Pooled it
- No evidence of superiority in reducing outliers of component alignment for patient-specific instrumentation for total knee arthroplasty: a systematic review.Orthopaedic surgery · 2015Pooled it
- Does imageless computer-assisted TKA lead to improved rotational alignment or fewer outliers? A systematic review.Clinical orthopaedics and related research · 2014Pooled it
- Improved accuracy in computer-assisted unicondylar knee arthroplasty: a meta-analysis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2013Pooled it
- Alignment accuracy and functional outcomes between hand-held navigation and conventional instruments in TKA: a randomized controlled trial.BMC musculoskeletal disorders · 2022Trial
- Trial
- No difference in mid-term survival and clinical outcome between patient-specific and conventional instrumented total knee arthroplasty: a randomized controlled trial.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2019Trial
- Conventional versus computer-navigated TKA: a prospective randomized study.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2017Trial
- Similar migration in computer-assisted and conventional total knee arthroplasty.Acta orthopaedica · 2017Trial
- Minimally invasive and computer-assisted total knee arthroplasty versus conventional technique: a prospective, randomized study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2014Trial
- Computer-assisted surgery improves rotational positioning of the femoral component but not the tibial component in total knee arthroplasty.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2014Trial
- Small improvements in mechanical axis alignment achieved with MRI versus CT-based patient-specific instruments in TKA: a randomized clinical trial.Clinical orthopaedics and related research · 2014Trial
- Patient-specific computed tomography based instrumentation in total knee arthroplasty: a prospective randomized controlled study.International orthopaedics · 2014Trial
- Intraoperative fluoroscopy improves surgical precision in conventional TKA.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2014Trial
- Evaluation of the accuracy of a patient-specific instrumentation by navigation.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2013Trial
- Accuracy of manual instrumentation of tibial cutting guide in total knee arthroplasty.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2013Trial
- No difference between computer-assisted and conventional total knee arthroplasty: five-year results of a prospective randomised study.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2013Trial
52 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeComputer-assisted surgery has been proposed as a technique to improve implant alignment during total knee arthroplasty (TKA). However, there is still a debate over the accuracy of placing the femoral and tibial components using computer-assisted systems in TKA. The aim of this study is to establish whether computer-assisted surgery leads to superior mechanical leg axis and implant positioning than conventional technique in patients with primary TKA.
methodsMajor electronic databases were systematically searched to identify relevant studies without language restriction. A meta-analysis of 41 randomized controlled trials (RCTs) or quasi-RCTs was performed in a random effects model. A subgroup analysis was conducted by type of navigation system to explore the clinical heterogeneity between these trials. The following radiographic parameters were used to compare computer-assisted surgery with conventional technique: (1) mechanical leg axis, (2) femoral component coronal alignment, (3) tibial component coronal alignment, (4) femoral component sagittal alignment, and (5) tibial component sagittal alignment.
resultsFor the mechanical leg axis and coronal positioning of femoral and tibial components, there are statistically significant reductions in the number of patients with malalignment in the CAS group if the outlier cutoff value is ±3 or 2° in the coronal and sagittal planes, respectively. Subgroup analysis demonstrates that CT-free navigation systems provide better alignment than conventional techniques in the coronal and sagittal alignment of femoral components within ±3 and 2°. If the outlier cutoff value for the tibial sagittal alignment is ±2°, the outlier percentages are higher in the CT-free navigation group than in the conventional group. However, there was no significant difference in the tibial sagittal alignment at ±3°.
conclusionComputer-assisted surgery does improve mechanical leg axis and component orientation in TKAs. However, high-quality RCTs are necessary to determine whether surgeons could use computer-assisted techniques to achieve a targeted tibial slope in TKA. LEVEL OF EVIDENCE: Therapeutic study (Systematic review of Level I/II studies), Level II.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.