Evidence map›Paper›PMID 21731825›Full record

Trial reportInternational forum of allergy & rhinology

Smoking and endoscopic sinus surgery: does smoking volume contribute to clinical outcome.

Luke Rudmik, Jess C Mace, Timothy L Smith

Abstract readClinical TrialMulticenter Study
In one paragraph

Trial report in International forum of allergy & rhinology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Prospective, randomized, controlled, open-label study to compare efficacy of a mineral-rich solution vs normal saline after complete ethmoidectomy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2019
    Trial
  2. Sinonasal Packing is Not a Requisite for Successful Cerebrospinal Fluid Leak Repair.Journal of neurological surgery. Part B, Skull base · 2022
    Article
  3. Evaluating the Efficacy and Trend of Sinus Surgery.International archives of otorhinolaryngology · 2020
    Article
  4. Article
  5. Article
  6. Observational
  7. Observational
  8. Article
  9. Olfactory-specific quality of life outcomes after endoscopic sinus surgery.International forum of allergy & rhinology · 2016
    Article
  10. Risk Factors and Comorbidities in Chronic Rhinosinusitis.Current allergy and asthma reports · 2016
    Review
  11. Article
  12. Review
  13. Comprehensive review on endonasal endoscopic sinus surgery.GMS current topics in otorhinolaryngology, head and neck surgery · 2015
    Review
  14. Predictors of quality of life outcomes in chronic rhinosinusitis after sinus surgery.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2014
    Article
  15. ICON: chronic rhinosinusitis.The World Allergy Organization journal · 2014
    Article
  16. Sino-nasal outcome test (SNOT-22): a predictor of postsurgical improvement in patients with chronic sinusitis.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2013
    Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Luke RudmikDivision of Rhinology and Sinus Surgery, Oregon Sinus Center, Department of Otolaryngology–Head and Neck Surgery, Oregon Health and Science University, Portland, OR 97239, USA.
Jess C Mace
Timothy L Smith

Funding

DETERMINANTS OF SURGICAL OUTCOMES IN CHRONIC SINUSITISR01DC005805 · NIDCD · OREGON HEALTH & SCIENCE UNIVERSITY · PI SMITH, TIMOTHY L, SOLER, ZACHARY M · 2004 to 2020
$7.6M
NIDCD NIH HHS R01 DC005805
6 · The paper itself

Abstract

backgroundThe effect of tobacco smoking on chronic rhinosinusitis (CRS) is not yet well-delineated. The purpose of this investigation was to evaluate the overall effect of smoking on postoperative outcomes (endoscopic score and health-related quality-of-life [HRQoL]) after endoscopic sinus surgery (ESS) for CRS and to determine if volume of daily smoking impacts outcomes.

methodsA total of 784 patients with CRS were prospectively enrolled between January 2001 and April 2009 after electing ESS from 1 of 3 academic tertiary care centers. Follow-up longer than 6 months was available on 39 smoking patients. Smoking volume (cigarettes/day) analysis was performed by dichotomizing patients into either of 2 subgroups: light smokers (<20 cigarettes per day) or heavy smokers (≥ 20 cigarettes per day). Primary outcomes were Lund-Kennedy endoscopy scores and 2 disease-specific HRQoL instruments: the Rhinosinusitis Disability Index (RSDI) and Chronic Sinusitis Survey (CSS).

resultsSmokers and nonsmokers experienced similar improvement in HRQoL following surgery (RSDI: p = 0.792 and CSS: p = 0.117). No difference in HRQoL improvements between light smokers and heavy smokers was identified. While overall changes in endoscopy scores did not differ between smokers and nonsmokers, there was a significant difference in the prevalence of worsening postoperative endoscopy scores between heavy smokers, light smokers, and nonsmokers (100%, 33%, and 20%, respectively; p = 0.002).

conclusionActive smoking status does not alter postoperative improvement in HRQoL after ESS. Although limited by a small sample size, increasing smoking volume may contribute to worse postoperative endoscopy scores.

Indexed as

EndoscopyAdultAgedChronic DiseaseFemaleHumansMaleMiddle AgedPostoperative ComplicationsProspective StudiesQuality of LifeRhinitisSinusitisSmokingTreatment Outcomeendoscopyquality of lifesinusitisSmokingtobacco

Identifiers

PMID21731825
PMCPMC3124774

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.