ArticlePloS one2011
N. elongata produces type IV pili that mediate interspecies gene transfer with N. gonorrhoeae.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Neisseria subflava Type 6 Secretion System competition with bacterial and fungal species.Applied microbiology and biotechnology · 2026Article
- Rationale and Ethical Assessment of an Oropharyngeal Gonorrhea Controlled Human Infection Model.The Journal of infectious diseases · 2025Article
- Antimicrobial susceptibilities of oral Neisseria from men on HIV pre-exposure prophylaxis in Hanoi, Vietnam.Journal of global antimicrobial resistance · 2025Article
- Carriage and antimicrobial susceptibility of commensal Neisseria species from the human oropharynx.Scientific reports · 2024Article
- Type IV pilus retraction is required formBio · 2024Article
- Cave Thiovulum (Candidatus Thiovulum stygium) differs metabolically and genomically from marine species.The ISME journal · 2023Article
- Horizontal Gene Transfer of Fluoroquinolone Resistance-Conferring Genes From CommensalFrontiers in microbiology · 2022Article
- Review
- Gonococcal invasion into epithelial cells depends on both cell polarity and ezrin.PLoS pathogens · 2021Article
- Type VI secretion system killing by commensaleLife · 2021Article
- Genomic analysis of Neisseria elongata isolate from a patient with infective endocarditis.FEBS open bio · 2021Article
- Virulence genes and previously unexplored gene clusters in four commensalMicrobial genomics · 2020Article
- Identification of integrative and conjugative elements in pathogenic and commensalMicrobial genomics · 2020Article
- Commensal Neisseria Kill Neisseria gonorrhoeae through a DNA-Dependent Mechanism.Cell host & microbe · 2019Article
- RpoN and the Nps and Npa two-component regulatory system control pilE transcription in commensal Neisseria.MicrobiologyOpen · 2019Article
- Article
- The Vibrio cholerae Minor Pilin TcpB Initiates Assembly and Retraction of the Toxin-Coregulated Pilus.PLoS pathogens · 2016Article
- Isolation and characterization of Neisseria musculi sp. nov., from the wild house mouse.International journal of systematic and evolutionary microbiology · 2016Article
- Neisseria cinerea isolates can adhere to human epithelial cells by type IV pilus-independent mechanisms.Microbiology (Reading, England) · 2016Article
- Characterization of a Unique Tetrasaccharide and Distinct Glycoproteome in the O-Linked Protein Glycosylation System of Neisseria elongata subsp. glycolytica.Journal of bacteriology · 2016Article
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7 authors.
Funding
Abstract
The genus Neisseria contains at least eight commensal and two pathogenic species. According to the Neisseria phylogenetic tree, commensals are basal to the pathogens. N. elongata, which is at the opposite end of the tree from N. gonorrhoeae, has been observed to be fimbriated, and these fimbriae are correlated with genetic competence in this organism. We tested the hypothesis that the fimbriae of N. elongata are Type IV pili (Tfp), and that Tfp functions in genetic competence. We provide evidence that the N. elongata fimbriae are indeed Tfp. Tfp, as well as the DNA Uptake Sequence (DUS), greatly enhance N. elongata DNA transformation. Tfp allows N. elongata to make intimate contact with N. gonorrhoeae and to mediate the transfer of antibiotic resistance markers between these two species. We conclude that Tfp functional for genetic competence is a trait of a commensal member of the Neisseria genus. Our findings provide a mechanism for the horizontal gene transfer that has been observed among Neisseria species.
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