ArticlePloS one2011
Genome-wide profiling of microRNAs in adipose mesenchymal stem cell differentiation and mouse models of obesity.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
25 citing papers in PubMed, 54 citations in OpenAlex.
- Circulating miR-130b mediates metabolic crosstalk between fat and muscle in overweight/obesity.Diabetologia · 2013Trial
- Adipocyte Precursor-Derived NRG1 Promotes Resistance to FGFR Inhibition in Urothelial Carcinoma.Cancer research · 2024Article
- Molecular and Cellular Mechanisms of Intramuscular Fat Development and Growth in Cattle.International journal of molecular sciences · 2024Review
- Article
- Micro-Executor of Natural Products in Metabolic Diseases.Molecules (Basel, Switzerland) · 2023Review
- Single-cell transcriptome dataset of human and mouse in vitro adipogenesis models.Scientific data · 2023Article
- Adipose-derived stem cells and obesity: The spear and shield relationship.Genes & diseases · 2023Review
- Influence of adenovirus 36 seropositivity on the expression of adipogenic microRNAs in obese subjects.International journal of obesity (2005) · 2020Article
- Expression profiling and analysis of some miRNAs in subcutaneous white adipose tissue during development of obesity.Genes & nutrition · 2020Article
- Dexamethasone induced miR-155 up-regulation in differentiating 3T3-L1 preadipocytes does not affect adipogenesis.Scientific reports · 2018Article
- Screening for PPAR Non-Agonist Ligands Followed by Characterization of a Hit, AM-879, with Additional No-Adipogenic and cdk5-Mediated Phosphorylation Inhibition Properties.Frontiers in endocrinology · 2018Article
- [MiR-218 Inhibits Migration and Invasion of Lung Cancer Cell by Regulating Robo1 Expression].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2017Article
- Mesenchymal Stem Cells Deliver Exogenous MicroRNA-let7c via Exosomes to Attenuate Renal Fibrosis.Molecular therapy : the journal of the American Society of Gene Therapy · 2016Article
- miR-148a is a downstream effector of X-box-binding protein 1 that silences Wnt10b during adipogenesis of 3T3-L1 cells.Experimental & molecular medicine · 2016Article
- JMJD3 as an epigenetic regulator in development and disease.The international journal of biochemistry & cell biology · 2015Review
- MicroRNA 665 Regulates Dentinogenesis through MicroRNA-Mediated Silencing and Epigenetic Mechanisms.Molecular and cellular biology · 2015Article
- miR-125a-3p and miR-483-5p promote adipogenesis via suppressing the RhoA/ROCK1/ERK1/2 pathway in multiple symmetric lipomatosis.Scientific reports · 2015Article
- Expression of pref-1/dlk-1 is regulated by microRNA-143 in 3T3-L1 cells.Molecular biology reports · 2015Article
- microRNAs as regulators of adipogenic differentiation of mesenchymal stem cells.Stem cells and development · 2015Review
- MIR146A inhibits JMJD3 expression and osteogenic differentiation in human mesenchymal stem cells.FEBS letters · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
In recent years, there has been accumulating evidence that microRNAs are key regulator molecules of gene expression. The cellular processes that are regulated by microRNAs include e.g. cell proliferation, programmed cell death and cell differentiation. Adipocyte differentiation is a highly regulated cellular process for which several important regulating factors have been discovered, but still not all are known to fully understand the underlying mechanisms. In the present study, we analyzed the expression of 597 microRNAs during the differentiation of mouse mesenchymal stem cells into terminally differentiated adipocytes by real-time RT-PCR. In total, 66 miRNAs were differentially expressed in mesenchymal stem cell-derived adipocytes compared to the undifferentiated progenitor cells. To further study the regulation of these 66 miRNAs in white adipose tissue in vivo and their dependence on PPARγ activity, mouse models of genetically or diet induced obesity as well as a mouse line expressing a dominant negative PPARγ mutant were employed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.