Evidence map›Paper›PMID 21731470›Full record

ArticleTherapy (London, England : 2004)2011

Functional abdominal pain and irritable bowel syndrome in children and adolescents.

Eric Chiou, Samuel Nurko

Abstract read
In one paragraph

Article in Therapy (London, England : 2004), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  13. Gastrointestinal symptoms predictors of health-related quality of life in pediatric patients with functional gastrointestinal disorders.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Eric ChiouCenter for Motility & Functional Gastrointestinal Disorders, Children's, Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA.
Samuel Nurko

Funding

Patient Oriented Research in Pediatric Motility and Related DisordersK24DK082792 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI NURKO, SAMUEL · 2009 to 2013
$923k
NIDDK NIH HHS K24 DK082792
6 · The paper itself

Abstract

Functional abdominal pain (FAP) and irritable bowel syndrome (IBS) are both associated with recurrent abdominal pain and are among the most commonly diagnosed medical problems in pediatrics. The majority of patients with mild complaints improve with reassurance and time. For a distinct subset of patients with more severe and disabling illness, finding effective treatment for these disorders remains a challenge. Based on the biopsychosocial model of functional disease, the Rome III criteria have helped frame FAP and IBS in terms of being a positive diagnosis and not a diagnosis of exclusion. However, the lack of a single, proven intervention highlights the complex interplay of pathologic mechanisms likely involved in the development of childhood FAP and IBS and the need for a multidisciplinary, integrated approach. This article discusses the epidemiology, proposed mechanisms, clinical approach and therapeutic options for the management of FAP and IBS in children and adolescents.

Identifiers

PMID21731470
PMCPMC3127202

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.