Evidence map›Paper›PMID 21731427›Full record

ArticleInternational journal of mass spectrometry2011

Simulation of Duty Cycle-Based Trapping and Ejection of Massive Ions Using Linear Digital Quadrupoles: the Enabling Technology for High Resolution Time-of-Flight Mass Spectrometry in the Ultra High Mass Range.

Jeonghoon Lee, Maxwell A Marino, Hideya Koizumi, Peter T A Reilly

Abstract read
In one paragraph

Article in International journal of mass spectrometry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Implementing Digital-Waveform Technology for ExtendedJournal of the American Society for Mass Spectrometry · 2021
    Article
  3. Article
  4. Digital Waveform Technology and the Next Generation of Mass Spectrometers.Journal of the American Society for Mass Spectrometry · 2018
    Article
  5. Constant-momentum acceleration time-of-flight mass spectrometry with energy focusing.Journal of the American Society for Mass Spectrometry · 2013
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jeonghoon LeeDepartment of Chemistry, Washington State University, Pullman, Washington 99164.
Maxwell A Marino
Hideya Koizumi
Peter T A Reilly

Funding

Accurate Mass Analysis of Singly-Charged Intact ProteinsR01GM088501 · NIGMS · WASHINGTON STATE UNIVERSITY · PI REILLY, PETER T. A. · 2009 to 2010
$572k
NIGMS NIH HHS R01 GM088501
6 · The paper itself

Abstract

Duty cycle-based trapping and extraction processes have been investigated for linear digitally-driven multipoles by simulating ion trajectories. The duty cycles of the applied waveforms were adjusted so that an effective trapping or ejection electric field was created between the rods and the grounded end cap electrodes. By manipulating the duty cycles of the waveforms, the potentials of the multipole rods can be set equal for part of the waveform cycle. When all rods are negative for this period, the device traps positive ions and when all are positive, it ejects them in focused trajectories. Four Linac II electrodes[1] have been added between the quadrupole rods along the asymptotes to create an electric field along the symmetry axis for collecting the ions near the exit end cap electrode and prompt ejection. This method permits the ions to be collected and then ejected in a concentrated and collimated plug into the acceleration region of a time-of-flight mass spectrometer (TOFMS). Our method has been shown to be independent of mass. Because the resolution of orthogonal acceleration TOFMS depends primarily on the dispersion of the ions injected into the acceleration region and not on the ion mass, this technology will enable high resolution in the ultrahigh mass range (m/z > 20,000).

Identifiers

PMID21731427
PMCPMC3126150

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.