ArticleJournal of global infectious diseases2011
River blindness: an old disease on the brink of elimination and control.
Article in Journal of global infectious diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Doxycycline plus ivermectin versus ivermectin alone for treatment of patients with onchocerciasis.The Cochrane database of systematic reviews · 2016Pooled it
- Ivermectin for onchocercal eye disease (river blindness).The Cochrane database of systematic reviews · 2012Pooled it
- Molecular Epidemiology of Skin-Dwelling Filariae and Risk Factors for Mansonella streptocerca Infection, Gabon.Emerging infectious diseases · 2026Article
- Article
- Wonder drugs and where to use them: a forecast of ivermectin's impact on malaria in Africa.Infectious Disease Modelling · 2025Article
- Repurposing of Anti-Infectives for the Management of Onchocerciasis Using Machine Learning and Protein Docking Studies.Bioinformatics and biology insights · 2025Article
- Significant reduction of blackfly densities in persistent onchocerciasis area following pilot implementation of an environment friendly approach (Slash and Clear).Scientific reports · 2024Article
- A Systematic Review on Suitability of Molecular Techniques for Diagnosis and Research into Infectious Diseases of Concern in Resource-Limited Settings.Current issues in molecular biology · 2022Review
- Relationship between skin snip and Ov16 ELISA: Two diagnostic tools for onchocerciasis in a focus in Cameroon after two decades of ivermectin-based preventive chemotherapy.PLoS neglected tropical diseases · 2022Article
- Ecological assessment of Black Fly (Simuliumdamnosum, Sensulato) breeding sites in two tributaries of Ogun river, Ogun state, Nigeria.Environmental monitoring and assessment · 2022Article
- Onchocerciasis Fingerprints in the Geriatric Population: Does Host Immunity Play a Role?Tropical medicine and infectious disease · 2021Review
- Filaricidal activity of Daniellia oliveri and Psorospermum febrifugum extracts.Parasites & vectors · 2021Article
- Computational Design and Preliminary Serological Analysis of a Novel Multi-Epitope Vaccine Candidate against Onchocerciasis and Related Filarial Diseases.Pathogens (Basel, Switzerland) · 2021Article
- The Mbam drainage system and onchocerciasis transmission post ivermectin mass drug administration (MDA) campaign, Cameroon.PLoS neglected tropical diseases · 2021Article
- Honoring antiparasitics: The 2015 Nobel Prize in Physiology or Medicine.Biomedical journal · 2016Review
- Co-endemicity of loiasis and onchocerciasis in rain forest communities in southwestern Nigeria.PLoS neglected tropical diseases · 2015Article
- Serosurveillance to monitor onchocerciasis elimination: the Ugandan experience.The American journal of tropical medicine and hygiene · 2014Article
- Validation of a remote sensing model to identify Simulium damnosum s.l. breeding sites in Sub-Saharan Africa.PLoS neglected tropical diseases · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For decades, onchocerciasis (or river blindness) was one of the most common infectious causes of blindness in the world. Primarily an infection of Africa, with limited distribution in the new world, disease due to the nematode Onchocerca volvulus is rapidly diminishing as a result of large public health campaigns targeting at risk populations in Africa and the Americas. Existing and newly-developed treatment strategies offer the chance to eliminate onchocercal ocular morbidity in some parts of the world. This article reviews these treatment strategies, current clinical and epidemiologic aspects of onchocerciasis, and the next steps toward elimination.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.