ArticleBioscience2011
Microbial Communities as Experimental Units.
Article in Bioscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- The effectiveness of artificial microbial community selection: a conceptual framework and a meta-analysis.Frontiers in microbiology · 2023Article
- Guided by the principles of microbiome engineering: Accomplishments and perspectives for environmental use.mLife · 2022Review
- The Clash of Microbiomes: From the Food Matrix to the Host Gut.Microorganisms · 2022Article
- Artificial Selection on Microbiomes To Breed Microbiomes That Confer Salt Tolerance to Plants.mSystems · 2021Article
- Article
- Engineering complex communities by directed evolution.Nature ecology & evolution · 2021Article
- Directed Evolution of Microbial Communities.Annual review of biophysics · 2021Review
- Eco-evolutionary dynamics of nested Darwinian populations and the emergence of community-level heredity.eLife · 2020Article
- Understanding the evolution of interspecies interactions in microbial communities.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Article
- Artificially selecting microbial communities: If we can breed dogs, why not microbiomes?PLoS biology · 2019Article
- Understanding microbial community dynamics to improve optimal microbiome selection.Microbiome · 2019Article
- Simulations reveal challenges to artificial community selection and possible strategies for success.PLoS biology · 2019Article
- An Experimental Framework for Generating Evolvable Chemical Systems in the Laboratory.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2017Article
- Geographical structure of endosymbiotic bacteria hosted by Bathymodiolus mussels at eastern Pacific hydrothermal vents.BMC evolutionary biology · 2017Article
- Composition and Functional Specialists of the Gut Microbiota of Frogs Reflect Habitat Differences and Agricultural Activity.Frontiers in microbiology · 2017Article
- Antibiotic resistance shaping multi-level population biology of bacteria.Frontiers in microbiology · 2013Article
- Temporal variation and lack of host specificity among bacterial endosymbionts of Osedax bone worms (Polychaeta: Siboglinidae).BMC evolutionary biology · 2012Article
- Is the pan-genome also a pan-selectome?F1000Research · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Artificial ecosystem selection is an experimental technique that treats microbial communities as though they were discrete units by applying selection on community-level properties. Highly diverse microbial communities associated with humans and other organisms can have significant impacts on the health of the host. It is difficult to find correlations between microbial community composition and community-associated diseases, in part because it may be impossible to define a universal and robust species concept for microbes. Microbial communities are composed of potentially thousands of unique populations that evolved in intimate contact, so it is appropriate in many situations to view the community as the unit of analysis. This perspective is supported by recent discoveries using metagenomics and pangenomics. Artificial ecosystem selection experiments can be costly, but they bring the logical rigor of biological model systems to the emerging field of microbial community analysis.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.