ReviewEuropean journal of clinical nutrition2011
Calcium and vitamin D for obesity: a review of randomized controlled trials.
Review in European journal of clinical nutrition, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 4 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- Are there prophylactic effects of vitamin D among healthier adult patients? A systematic review of randomized controlled trials.BMC nutrition · 2025Pooled it
- Vitamin D supplementation and body fat mass: a systematic review and meta-analysis.European journal of clinical nutrition · 2018Pooled it
- Non-skeletal health effects of vitamin D supplementation: A systematic review on findings from meta-analyses summarizing trial data.PloS one · 2017Pooled it
- Effect of vitamin D supplementation alone or with calcium on adiposity measures: a systematic review and meta-analysis of randomized controlled trials.Nutrition reviews · 2015Pooled it
- Effects of low-fat milk consumption at breakfast on satiety and short-term energy intake in 10- to 12-year-old obese boys.European journal of nutrition · 2016Trial
- Vitamin D3 supplementation during weight loss: a double-blind randomized controlled trial.The American journal of clinical nutrition · 2014Trial
- Calcium and vitamin D supplementation is associated with decreased abdominal visceral adipose tissue in overweight and obese adults.The American journal of clinical nutrition · 2012Trial
- The Nutritional Paradox of Obesity: Mechanisms and Clinical Implications of Micronutrient Deficiencies.Medical sciences (Basel, Switzerland) · 2026Review
- Sarcopenia in Type 2 Diabetes Mellitus: Study of the Modifiable Risk Factors Involved.Journal of clinical medicine · 2023Article
- A weighted quantile sum regression with penalized weights and two indices.Frontiers in public health · 2023Article
- Association between serum vitamin D levels and visceral adipose tissue among adolescents: a cross-sectional observational study in NHANES 2011-2015.BMC pediatrics · 2022Observational
- Development of a Short Questionnaire for the Screening for Vitamin D Deficiency in Italian Adults: The EVIDENCe-Q Project.Nutrients · 2022Article
- Associations between serum 25-hydroxyvitamin D, body mass index and body fat composition among Emirati population: Results from the UAE healthy future study.Frontiers in endocrinology · 2022Article
- Association of Vitamin D status with Visceral Adiposity Index and Lipid Accumulation Product Index among a Group of Iranian People.Clinical nutrition research · 2021Article
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- Effects of Vitamin D Status and Supplements on Anthropometric and Biochemical Indices in a Clinical Setting: A Retrospective Study.Nutrients · 2019Article
- Modelling the Effects of Beverage Substitution during Adolescence on Later Obesity Outcomes in Early Adulthood: Results from the Raine Study.Nutrients · 2019Article
- Anti-Obesity Effects of Dietary Calcium: The Evidence and Possible Mechanisms.International journal of molecular sciences · 2019Review
- Association between 25-Hydroxyvitamin D Status and Components of Body Composition and Glucose Metabolism in Older Men and Women.Nutrients · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity often coexists with low calcium intake and vitamin D insufficiency. There is emerging evidence of a role for these nutrients in the regulation of body weight. However, it is unclear whether increasing intakes of calcium and/or vitamin D during energy restriction, is a better strategy for weight and fat loss. We searched the literature from 2000 to date for randomized controlled trials (RCTs) on weight loss that had increased calcium or vitamin D per se, or in combination. Primary and secondary studies were included for this analysis. A total of 15 RCTs on calcium with or without vitamin D and seven on vitamin D alone met our criteria. Two studies reported that supplemental calcium significantly increased fat loss during caloric restriction by 1.8 and 2.2 kg, three found differences between 1 and 3.5 kg but were statistically nonsignificant, while nine trials were equivocal (±0.7 kg). The data on vitamin D supplementation during weight loss were too few to make firm conclusions. Current evidence from RCTs did not consistently support the contention that calcium and vitamin D accelerated weight or fat loss in obesity. There were studies that favoured the hypothesis but lacked the statistical power. There is a need for RCTs to examine the influence of vitamin D on body fat.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.