Evidence map›Paper›PMID 21730907›Full record

ArticleAdvances in neonatal care : official journal of the National Association of Neonatal Nurses2011

Necrotizing enterocolitis in the premature infant: neonatal nursing assessment, disease pathogenesis, and clinical presentation.

Katherine E Gregory, Christine E Deforge, Kristan M Natale, Michele Phillips, Linda J Van Marter

Abstract read
In one paragraph

Article in Advances in neonatal care : official journal of the National Association of Neonatal Nurses, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 2 syntheses or guidelines pooled it, 167 citations in OpenAlex.

  1. Pooled it
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  12. Finite Element Modeling of Abdominal Near-Infrared Spectroscopy for Infant Splanchnic Oximetry.International journal for numerical methods in biomedical engineering · 2025
    Article
  13. Article
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  16. Blood absolute monocyte count trends in preterm infants with suspected necrotizing enterocolitis: an adjunct tool for diagnosis?Journal of perinatology : official journal of the California Perinatal Association · 2024
    Article
  17. Article
  18. American journal of physiology. Gastrointestinal and liver physiology · 2024
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  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Katherine E GregoryBoston College, William F. Connell School of Nursing, Chestnut Hill, Massachusetts 02467, USA. katherine.gregory.2@bc.edu
Christine E Deforge
Kristan M Natale
Michele Phillips
Linda J Van Marter
Boston College · US

Funding

ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Takara Leah Stanley · 1994 to 2026
$31.6M
Biochemical Predictors of Necrotizing EnterocolitisK23NR011320 · NINR · BOSTON COLLEGE · PI GREGORY, KATHERINE ELIZABETH · 2009 to 2011
$387k
NHLBI NIH HHS HL 72931NIDDK NIH HHS P30 DK040561NINR NIH HHS K23 NR011320
6 · The paper itself

Abstract

Necrotizing enterocolitis (NEC) remains one of the most catastrophic comorbidities associated with prematurity. In spite of extensive research, the disease remains unsolved. The aims of this article are to present the current state of the science on the pathogenesis of NEC, summarize the clinical presentation and severity staging of the disease, and highlight the nursing assessments required for early identification of NEC and ongoing care for infants diagnosed with this gastrointestinal disease. The distributions of systemic and intestinal clinical signs that are most sensitive to nursing assessment and associated with Bell Staging Criteria are presented. These descriptive data are representative of 117 cases of NEC diagnosed in low-gestational-age infants (<29 weeks' gestation). The data highlight the clinical signs most commonly observed in infants with NEC and thus provide NICU nurses an evidence-based guide for assessment and care of infants with NEC.

Indexed as

Enterocolitis, NecrotizingInfant, Premature, DiseasesEnteral NutritionHumansInfant, NewbornInfant, PrematureNursing AssessmentRisk FactorsSeverity of Illness IndexTreatment Outcome

Identifiers

PMID21730907
PMCPMC3759524
OpenAlexW2148550105

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.