Evidence map›Paper›PMID 21730321›Full record

ReviewCirculation2011

Functional genomics applied to cardiovascular medicine.

Thomas P Cappola, Kenneth B Margulies

Abstract readReview
In one paragraph

Review in Circulation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. What Should a Clinical Cardiologist Know About Cardiogenetics?Journal of the American Heart Association · 2025
    Review
  2. Article
  3. Article
  4. Epigenomics and transcriptomics association study of blood pressure and incident diagnosis of hypertension in twins.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article
  5. Article
  6. The Role of CYP450 Drug Metabolism in Precision Cardio-Oncology.International journal of molecular sciences · 2020
    Review
  7. Functional Genomics and CRISPR Applied to Cardiovascular Research and Medicine.Arteriosclerosis, thrombosis, and vascular biology · 2019
    Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Ischemia/Reperfusion.Comprehensive Physiology · 2016
    Review
  14. Article
  15. Article
  16. Cardiovascular genomics: a biomarker identification pipeline.IEEE transactions on information technology in biomedicine : a publication of the IEEE Engineering in Medicine and Biology Society · 2012
    Review
  17. Article
  18. Article
  19. Cell biology of ischemia/reperfusion injury.International review of cell and molecular biology · 2012
    Review
  20. Transcriptomic biomarkers of cardiovascular disease.Progress in cardiovascular diseases
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Thomas P CappolaPenn Cardiovascular Institute and the Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA. thomas.cappola@uphs.upenn.edu
Kenneth B Margulies

Funding

Genomics of myocardial transcription factors in cardiac remodelingR01HL088577 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CAPPOLA, THOMAS P. · 2007 to 2013
$5.3M
Endogenous Cardiac Repair in HumansR01HL089847 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI MARGULIES, KENNETH BER · 2009 to 2012
$1.9M
Transcriptional modules in human heart failureR21HL092379 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CAPPOLA, THOMAS P., HANNENHALLI, SRIDHAR · 2008 to 2009
$433k
NHLBI NIH HHS R01 HL088577NHLBI NIH HHS R01HL088577NHLBI NIH HHS R01 HL089847NHLBI NIH HHS R01HL089847NHLBI NIH HHS R21 HL092379NHLBI NIH HHS R21HL092379
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Biomedical ResearchCardiovascular DiseasesComputational BiologyEpigenomicsGenomicsHumansPharmacogeneticsProteomics

Identifiers

PMID21730321
PMCPMC3138215

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.