SynthesisBMJ clinical evidence2010
Colic in infants.
Synthesis in BMJ clinical evidence, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Acupuncture treatments for infantile colic: a systematic review and individual patient data meta-analysis of blinding test validated randomised controlled trials.Scandinavian journal of primary health care · 2018Pooled it
- Manipulative therapies for infantile colic.The Cochrane database of systematic reviews · 2012Pooled it
- The effect of chiropractic treatment on infantile colic: study protocol for a single-blind randomized controlled trial.Chiropractic & manual therapies · 2018Trial
- Acupuncture for infantile colic: a blinding-validated, randomized controlled multicentre trial in general practice.Scandinavian journal of primary health care · 2013Trial
- Exploring Manual Interventions for Infantile Colic: A Scoping Review of the Evidence.Children (Basel, Switzerland) · 2025Review
- Biotics and Children's and Adolescents' Health: A Narrative Review.Children (Basel, Switzerland) · 2024Review
- Spinal manipulation and mobilisation in the treatment of infants, children, and adolescents: a systematic scoping review.BMC pediatrics · 2022Article
- Nine-Strain Bacterial Synbiotic Improves Crying and Lowers Fecal Calprotectin in Colicky Babies-An Open-Label Randomized Study.Microorganisms · 2022Article
- Hydrolysed Formulas in the Management of Cow's Milk Allergy: New Insights, Pitfalls and Tips.Nutrients · 2021Review
- Cow's Milk Allergy or Gastroesophageal Reflux Disease-Can We Solve the Dilemma in Infants?Nutrients · 2021Review
- Infantile Colic-The Perspective of German and Polish Pediatricians in 2020.International journal of environmental research and public health · 2020Article
- Cow's Milk Protein Allergy in Infancy: A Risk Factor for Functional Gastrointestinal Disorders in Children?Nutrients · 2018Review
- Recent advances in understanding and managing infantile colic.F1000Research · 2018Review
- Exploring hypotheses and rationale for causes of infantile colic.Neurogastroenterology and motility · 2017Review
- Costs associated with functional gastrointestinal disorders and related signs and symptoms in infants: a systematic review protocol.BMJ open · 2016Article
- Intestinal microbiota composition after antibiotic treatment in early life: the INCA study.BMC pediatrics · 2015Observational
- Suck, swallow and breathing coordination in infants with infantile colic.The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionColic in infants causes one in six families (17%) with children to consult a health professional. One systematic review of 15 community-based studies found a wide variation in prevalence, which depended on study design and method of recording. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical question: What are the effects of treatments for colic in infants? We searched: Medline, Embase, The Cochrane Library, and other important databases up to September 2009 (Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
resultsWe found 27 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
conclusionsIn this systematic review we present information relating to the effectiveness and safety of the following interventions: advice to increase carrying, advice to reduce stimulation, casein hydrolysate milk, cranial osteopathy, crib vibrator device, focused counselling, gripe water, infant massage, low-lactose milk, simethicone, soya-based infant feeds, spinal manipulation, and whey hydrolysate milk.
Indexed as
Identifiers
21729336PMC2907620What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.