SynthesisNature reviews. Urology2011
The placebo effect in overactive bladder syndrome.
Synthesis in Nature reviews. Urology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Pharmacologic treatment of pediatric headaches: a meta-analysis.JAMA pediatrics · 2013Pooled it
- Noninvasive NESA Microcurrent Neuromodulation for Refractory Overactive Bladder in Women: A Triple-Blind, Randomized, Sham-Controlled Pilot Trial.Medicina (Kaunas, Lithuania) · 2026Trial
- Pelvic Floor Muscle Training by Telehealth to Treat Female Stress Urinary Incontinence: A Randomized Clinical Trial.International urogynecology journal · 2026Trial
- Efficacy of high-dose vitamin D supplementation vs. solifenacin or standard urotherapy for overactive bladder dry in children: a secondary analysis of a randomized clinical trial.World journal of urology · 2024Trial
- Efficacy and safety of onabotulinumtoxinA in patients with overactive bladder: subgroup analyses by sex and by serum prostate-specific antigen levels in men from a randomized controlled trial.International urology and nephrology · 2021Trial
- Therapeutic efficacy and short-term durability of trans-urethral amniotic bladder injections for the treatment of refractory COVID-associated cystitis.Bladder (San Francisco, Calif.) · 2024Article
- A pilot trial of movement-based pelvic floor physical therapy to address pelvic floor myofascial pain and lower urinary tract symptoms.International urogynecology journal · 2023Article
- Posterior Tibial Nerve Stimulation in Children with Lower Urinary Tract Dysfunction: A Mixed-Methods Analysis of Experiences, Quality of Life and Treatment Effect.International journal of environmental research and public health · 2022Article
- The placebo and nocebo effects in functional urology.Nature reviews. Urology · 2022Review
- Mirabegron, alone and in combination, in the treatment of overactive bladder: real-world evidence and experience.Therapeutic advances in urology · 2018Review
- CUA guideline on adult overactive bladder.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2017Article
- Placebo Medication and Sham Surgery Responses in Benign Prostatic Hyperplasia Treatments: Implications for Clinical Trials.Current urology reports · 2015Review
- Management of nocturia in the female.Current urology reports · 2015Review
- [Chronic pollakiuria: cystectomy or psychotherapy].Der Urologe. Ausg. A · 2014Review
- Efficacy and safety of Baweidihuang-wan in women with overactive bladder: a randomized, double blind, placebo controlled trial.International journal of clinical and experimental medicine · 2014Article
- Overactive bladder syndrome: Current pathophysiological concepts and therapeutic approaches.Arab journal of urology · 2013Review
- Overactive bladder, differential diagnosis, and clinical utility of fesoterodine.International journal of general medicine · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Overactive bladder syndrome (OAB) is a condition that involves urinary urgency and affected individuals are usually treated with behavioral therapy and antimuscarinic agents as first-line therapies. Existing evidence from clinical trial data suggests that a positive placebo effect occurs in patients receiving treatment for OAB. In our systematic Review of placebo-controlled, randomized trials in OAB, we show statistically significant improvements in three patient-reported outcomes-incontinence episodes per day, micturition episodes per day and mean micturition volume from baseline-after placebo in randomized studies for OAB. The findings could highlight the brain's role in the pathophysiology of OAB or the role of additional bladder training conducted as part of OAB clinical trials. More research is needed to determine the underlying mechanisms of the placebo effect in OAB.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.