ArticleAnaerobe2011
Non-toxigenic Clostridium sordellii: clinical and microbiological features of a case of cholangitis-associated bacteremia.
Article in Anaerobe, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 21 citations in OpenAlex.
- FatalPathogens (Basel, Switzerland) · 2025Review
- Beyond the Ordinary: Paeniclostridium sordellii Osteomyelitis in a Young Male Patient From Pakistan.Clinical medicine insights. Case reports · 2024Article
- Detection and molecular characterization of Clostridium perfringens, Paeniclostridium sordellii and Clostridium septicum from lambs and goat kids with hemorrhagic abomasitis in Turkey.BMC veterinary research · 2023Article
- Persistent bacteremia and psoas abscess caused by a lethal toxin-deficient Paeniclostridiumsordellii.Anaerobe · 2022Article
- Prevalence and Antimicrobial Resistance ofAntibiotics (Basel, Switzerland) · 2021Article
- Infective Endocarditis Caused byJournal of laboratory physicians · 2021Article
- Article
- Non-lethal Clostridium sordellii bacteraemia in an immunocompromised patient with pleomorphic sarcoma.BMJ case reports · 2016Article
- Clostridium sordellii genome analysis reveals plasmid localized toxin genes encoded within pathogenicity loci.BMC genomics · 2015Article
- Foot infection by Clostridium sordellii: case report and review of 15 cases in France.Journal of clinical microbiology · 2015Article
- Evolutionary history of the Clostridium difficile pathogenicity locus.Genome biology and evolution · 2014Article
- Clostridium difficile ribotype diversity at six health care institutions in the United States.Journal of clinical microbiology · 2013Article
- Clostridium difficile ribotype does not predict severe infection.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2012Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
Abstract
Toxigenic Clostridium sordellii strains are increasingly recognized to cause highly lethal infections in humans that are typified by a toxic shock syndrome (TSS). Two glucosylating toxins, lethal toxin (TcsL) and hemorrhagic toxin (TcsH) are believed to be important in the pathogenesis of TSS. While non-toxigenic strains of C. sordellii demonstrate reduced cytotoxicity in vitro and lower virulence in animal models of infection, there are few data regarding their behavior in humans. Here we report a non-TSS C. sordellii infection in the context of a polymicrobial bacterial cholangitis. The C. sordellii strain associated with this infection did not carry either the TcsL-encoding tcsL gene or the tcsH gene for TcsH. In addition, the strain was neither cytotoxic in vitro nor lethal in a murine sepsis model. These results provide additional correlative evidence that TcsL and TcsH increase the risk of mortality during C. sordellii infections.
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Registered trials
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