SynthesisBMJ clinical evidence2009
Amblyopia.
Synthesis in BMJ clinical evidence, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- NEIVATECH pilot study: immersive virtual reality training in older amblyopic children with non-compliance or non-response to patching.Scientific reports · 2024Trial
- Comparative Effects of Monocular and Stereopsis Training on Visual Acuity and Stereoacuity in Children With Amblyopia.Investigative ophthalmology & visual science · 2026Article
- Surgical Outcomes in Partially Accommodative Esotropia Using Augmented Distance-Angle Averaging With and Without Hyperopic Correction.American journal of ophthalmology · 2026Article
- Combined Occlusion Therapy and Home-Based Perceptual Learning in Children with Persistent Amblyopia: A Longitudinal Case Series.Journal of clinical medicine · 2026Article
- Macular, Foveal and RNFL Thickness Patterns in Amblyopia: A Comparative Study.Clinical optometry · 2026Article
- Article
- Children with Additional Support Needs Risk Missing Out on Effective Vision Screening: Audit and Survey Considering Attendance Rates and Parent Reported Barriers to Service Access, including Recommendations for Improvement.The British and Irish orthoptic journal · 2025Article
- Landolt C-Tests With "Fixed" Arcmin Separations Detect Amblyopia But Underestimate Crowding in Moderate-to-Severe Amblyopic Children and Adults.Investigative ophthalmology & visual science · 2024Article
- Measuring the Interocular Delay and its Link to Visual Acuity in Amblyopia.Investigative ophthalmology & visual science · 2024Article
- Assessment of macular microvascular changes in children following treatment of anisometropic myopic amblyopia using optical coherence tomography angiography.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Observational
- The impact of eye dominance on fixation stability in school-aged children.Journal of eye movement research · 2023Article
- Outcome of superior manual small-incision cataract surgery in pediatric age group - A five year retrospective study at a tertiary eye hospital in Karnataka.Indian journal of ophthalmology · 2022Article
- Bilateral Medial Rectus Advancement versus Unilateral Medial Rectus Advancement with Lateral Rectus Recession for Surgical Management of Large Angle Consecutive Exotropia without Adduction Deficit.Clinical ophthalmology (Auckland, N.Z.) · 2022Article
- Current Management of Amblyopia with New Technologies for Binocular Treatment.Vision (Basel, Switzerland) · 2021Review
- Scottish Pre-School Vision Screening - First 3 Years of National Data.The British and Irish orthoptic journal · 2020Article
- The treatment of amblyopia: current practice and emerging trends.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAmblyopia is commonly associated with squint (strabismus) or refractive errors resulting in different visual inputs to each eye during the sensitive period of visual development (<7-8 years of age). The cumulative incidence is estimated at 2% to 4% in children aged up to 15 years. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of interventions to detect amblyopia early? What are the effects of medical treatments for amblyopia? We searched: Medline, Embase, The Cochrane Library, and other important databases up to May 2008 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations, such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
resultsWe found 16 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
conclusionsIn this systematic review, we present information relating to the effectiveness and safety of the following interventions: active vision therapy; glasses alone or with occlusion; or penalisation to treat amblyopia; and screening to detect amblyopia early.
Indexed as
Identifiers
21726480PMC2907781What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.