Evidence map›Paper›PMID 21726445›Full record

Trial reportBMC public health2011

A randomised controlled trial of extended brief intervention for alcohol dependent patients in an acute hospital setting (ADPAC).

Lynn Owens, Graham Butcher, Ian Gilmore, Ruwanthi Kolamunnage-Dona, James Oyee, Liz Perkins, Tom Walley, Paula Williamson, Ken Wilson, Munir Pirmohamed

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC public health, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01060397 nacompletednot on this map

A Randomized Controlled Trial of Extended Brief Interventions for Alcohol-dependent Patients in an Acute Care Setting

TypeinterventionalSponsorSouthport and Ormskirk Hospital NHS TrustRan2009 to 2013Enrolled267ConditionsAlcohol DependenceArmsExtended Brief Intervention, Control
NCT01934751 naunknown statusnot on this mapstarted 2013, after this paper: background citation

Randomized Controlled Trial on the Effectiveness of Immediate Versus Delayed Access to Hospital-based Addiction Services

TypeinterventionalSponsorWomen's College HospitalRan2013 to 2015Enrolled124ConditionsAlcohol Addiction, Opiate AddictionArmsDelayed Intervention (DI), Rapid Intervention (RI)
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Lynn OwensThe Wolfson Centre for Personalised Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, UK. lynno@liv.ac.uk
Graham Butcher
Ian Gilmore
Ruwanthi Kolamunnage-Dona
James Oyee
Liz Perkins
Tom Walley
Paula Williamson
Ken Wilson
Munir Pirmohamed
University of Liverpool · GBRoyal Liverpool and Broadgreen University Hospital NHS Trust · GBSouthport and Ormskirk Hospital NHS Trust · GB

Funding

Department of Health PB-PG-0408-15077
6 · The paper itself

Abstract

backgroundAlcohol dependence affects approximately 3% of the English population, and accounts for significant medical and psychiatric morbidity. Only 5.6% of alcohol-dependent individuals ever access specialist treatment and only a small percentage ever seek treatment. As people who are alcohol dependent are more likely to have experienced health problems leading to frequent attendance at acute hospitals it would seem both sensible and practical to ensure that this setting is utilised as a major access point for treatment, and to test the effectiveness of these treatments. METHODS/

designThis is a randomised controlled trial with a primary hypothesis that extended brief interventions (EBI) delivered to alcohol-dependent patients in a hospital setting by an Alcohol Specialist Nurse (ASN) will be effective when compared to usual care in reducing overall alcohol consumption and improving on the standard measures of alcohol dependence. Consecutive patients will be screened for alcohol misuse in the Emergency Department (ED) of a district general hospital. On identification of an alcohol-related problem, following informed written consent, we aim to randomize 130 patients per group. The ASN will discharge to usual clinical care all control group patients, and plan a programme of EBI for treatment group patients. Follow-up interview will be undertaken by a researcher blinded to the intervention at 12 and 24 weeks. The primary outcome measure is level of alcohol dependence as determined by the Severity of Alcohol Dependence Questionnaire (SADQ) score. Secondary outcome measures include; Alcohol Use Disorders Identification Test (AUDIT) score, quantity and frequency of alcohol consumption, health-related quality of life measures, service utilisation, and patient experience. The trial will also allow an assessment of the cost-effectiveness of EBI in an acute hospital setting. In addition, patient experience will be assessed using qualitative methods. DISCUSSION: This paper presents a protocol for a RCT of EBI delivered to alcohol dependent patients by an ASN within an ED. Importantly; the trial will also seek to understand patients' perceptions and experiences of being part of a RCT and of receiving this form of intervention. TRIAL REGISTRATION NUMBER: ISRCTN: ISRCTN78062794.

Indexed as

Emergency Service, HospitalPatientsAdolescentAdultAlcoholismEnglandFemaleHumansInterviews as TopicMaleMiddle AgedSeverity of Illness IndexState MedicineYoung Adult

Identifiers

PMID21726445
PMCPMC3141470
OpenAlexW1976409452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.