ArticleMolecular plant pathology2011
Negative regulation of defence signalling pathways by the EDR1 protein kinase.
Article in Molecular plant pathology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 46 citations in OpenAlex.
- An integrated QTL-GWAS approach fine-maps a major locus (qMWS3 - 2) for stable resistance to maize white spot in tropical germplasm.BMC plant biology · 2026Article
- Signaling Pathway Analysis and Downstream Genes Associated with Disease Resistance Mediated byPlants (Basel, Switzerland) · 2026Article
- Transcriptomic and physiological effects of superabsorbent polymer seed coating on maize under drought stress.Frontiers in plant science · 2026Article
- Designed gRNAs for CRISPR-Cas9 based antifungal resistance in eggplant.Bioinformation · 2023Article
- Comparative Analysis of Alternative Splicing in Two Contrasting Apple Cultivars Defense againstInternational journal of molecular sciences · 2022Article
- Identification of Raf-Like Kinases B Subfamily Genes inInternational journal of molecular sciences · 2021Article
- Epidermal chloroplasts are defense-related motile organelles equipped with plant immune components.Nature communications · 2021Article
- OXR2 Increases Plant Defense against a Hemibiotrophic Pathogen via the Salicylic Acid Pathway.Plant physiology · 2020Article
- Loss of the Acetyltransferase NAA50 Induces Endoplasmic Reticulum Stress and Immune Responses and Suppresses Growth.Plant physiology · 2020Article
- Article
- Arabidopsis MAPKKK δ-1 is required for full immunity against bacterial and fungal infection.Journal of experimental botany · 2020Article
- Article
- Identification and expression analysis ofPeerJ · 2018Article
- Membrane Trafficking in Plant Immunity.Molecular plant · 2017Review
- Two Different Transcripts of a LAMMER Kinase Gene Play Opposite Roles in Disease Resistance.Plant physiology · 2016Article
- Biotrophy at Its Best: Novel Findings and Unsolved Mysteries of the Arabidopsis-Powdery Mildew Pathosystem.The arabidopsis book · 2016Article
- The Arabidopsis EDR1 protein kinase negatively regulates the ATL1 E3 ubiquitin ligase to suppress cell death.The Plant cell · 2014Article
- A mutation in a coproporphyrinogen III oxidase gene confers growth inhibition, enhanced powdery mildew resistance and powdery mildew-induced cell death in Arabidopsis.Plant cell reports · 2013Article
- A model for the biosynthesis and transport of plasma membrane-associated signaling receptors to the cell surface.Frontiers in plant science · 2012Article
- The KEEP ON GOING protein of Arabidopsis recruits the ENHANCED DISEASE RESISTANCE1 protein to trans-Golgi network/early endosome vesicles.Plant physiology · 2011Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The enhanced disease resistance 1 (edr1) mutant of Arabidopsis confers enhanced resistance to bacterial and fungal pathogens. To better understand how edr1-mediated resistance occurs, we performed transcriptome analyses on wild-type and edr1 plants inoculated with the fungal pathogen Golovinomyces cichoracearum (powdery mildew). The expression of many known and putative defence-associated genes was more rapidly induced, and to higher levels, in edr1 plants relative to the wild-type. Many of the genes with elevated expression encoded WRKY transcription factors and there was enrichment for their binding sites in promoters of the genes upregulated in edr1. Confocal microscopy of transiently expressed EDR1 protein showed that a significant fraction of EDR1 was localized to the nucleus, suggesting that EDR1 could potentially interact with transcription factors in the nucleus. Analysis of gene ontology annotations revealed that genes associated with the endomembrane system, defence, reactive oxygen species (ROS) production and protein kinases were induced early in the edr1 mutant, and that elevated expression of the endomembrane system, defence and ROS-related genes was maintained for at least 4 days after infection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.