ReviewInternational dental journal2011
Dental caries pathogenicity: a genomic and metagenomic perspective.
Review in International dental journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 73 citations in OpenAlex.
- pH-OBiofilm · 2026Article
- Oral-Rinse-Sourced Microbiota in Oral Health and Diseases in a Representative US Adult Population: Implications for Diagnostics.Journal of clinical periodontology · 2026Article
- Construction of caries risk assessment scale and oral microecology analysis of adolescents with fixed orthodontic treatment.BMC oral health · 2026Article
- Metagenomics as an Effective Diagnostic Approach for Exploring Oral Microbial Diversity and Dental Diseases: A Narrative Review.International journal of clinical pediatric dentistry · 2026Review
- Supragingival microbial profiles in caries-free and caries-active adolescents treated with fixed orthodontics.Current research in microbial sciences · 2025Article
- How probiotics, prebiotics, synbiotics, and postbiotics prevent dental caries: an oral microbiota perspective.NPJ biofilms and microbiomes · 2024Review
- The Evolving Microbiome of Dental Caries.Microorganisms · 2024Review
- A Longitudinal Metagenomic Comparative Analysis of Oral Microbiome Shifts in Patients Receiving Proton Radiation versus Photon Radiation for Head and Neck Cancer.Journal of cancer & allied specialties · 2024Article
- An Effective Shrinkage Control Method for Tooth Profile Accuracy Improvement of Micro-Injection-Molded Small-Module Plastic Gears.Polymers · 2022Article
- A comparison of the composition and functions of the oral and gut microbiotas in Alzheimer's patients.Frontiers in cellular and infection microbiology · 2022Article
- Effectiveness of Propolis in the Treatment of Periodontal Disease: Updated Systematic Review with Meta-Analysis.Antioxidants (Basel, Switzerland) · 2021Review
- Oral Microbiome Alterations Associated with Early Childhood Caries Highlight the Importance of Carbohydrate Metabolic Activities.mSystems · 2019Article
- Embracing Personalized Medicine in Dentistry.Journal of pharmacy & bioallied sciences · 2019Review
- Functional dysbiosis within dental plaque microbiota in cleft lip and palate patients.Progress in orthodontics · 2019Article
- Article
- Oxidative stress in the oral cavity is driven by individual-specific bacterial communities.NPJ biofilms and microbiomes · 2018Article
- Effects of a New Nano-Silver Fluoride-Containing Dentifrice on Demineralization of Enamel andInternational journal of dentistry · 2018Article
- Dental plaque microbial profiles of children from Khartoum, Sudan, with congenital heart defects.Journal of oral microbiology · 2017Article
- Acidogenicity and acid tolerance ofJournal of oral microbiology · 2016Article
- A study on β-defensin-2 and histatin-5 as a diagnostic marker of early childhood caries progression.Biological research · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
In this review we address the subject of dental caries pathogenicity from a genomic and metagenomic perspective. The application of genomic technologies is certain to yield novel insights into the relationship between the bacterial flora, dental health and disease. Three primary attributes of bacterial species are thought to have direct impact on caries development, these include: adherence on tooth surfaces (biofilm formation), acid production and acid tolerance. Attempts to define the specific aetiological agents of dental caries have proven to be elusive, supporting the notion that caries aetiology is perhaps complex and multi-faceted. The recently introduced Human Microbiome Project (HMP) that endeavors to characterise the micro-organisms living in and on the human body is likely to shed new light on these questions and improve our understanding of polymicrobial disease, microbial ecology in the oral cavity and provide new avenues for therapeutic and molecular diagnostics developments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.