ArticleActa neurochirurgica. Supplement2011
Brain arteriovenous malformation pathogenesis: a response-to-injury paradigm.
Article in Acta neurochirurgica. Supplement, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
65 citing papers in PubMed, 1 synthesis or guideline pooled it, 125 citations in OpenAlex.
- Reporting of angiographic studies in patients diagnosed with a cerebral arteriovenous malformation: a systematic review.F1000Research · 2023Pooled it
- Needle trauma as a trigger for clinical manifestation of a pre-existing venous malformation: a case report.Journal of surgical case reports · 2026Article
- Article
- Pediatric cerebral arteriovenous malformation diagnosed 11 years after neonatal thalamic hemorrhage: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Association of Plasma Inflammatory Proteins and Intracerebral Hemorrhage in Pediatric Brain Arteriovenous Malformations.Pediatric stroke · 2025Article
- Lesion-Filling Index from Quantitative DSA Correlates with Hemorrhage of Cerebral AVM.AJNR. American journal of neuroradiology · 2024Article
- CNS resident macrophages enhance dysfunctional angiogenesis and circulating monocytes infiltration in brain arteriovenous malformation.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024Article
- Nidus Compacity Determined by Semi-Automated Segmentation is a Strong Quantitative Predictor of Brain Arterio-Venous Malformation Cure.Clinical neuroradiology · 2023Article
- Case report: A combination of nitroglycerin and adenosine proves effective in repairing a cerebral arteriovenous malformation.Frontiers in neurology · 2023Article
- Benefits from Exclusion Treatment of Unruptured Brain Arteriovenous Malformations on Epilepsy in Adults.Clinical neuroradiology · 2022Observational
- De novo brain AVM following radiotherapy for cerebral cavernous malformation in a child: A 15-year clinical course.The neuroradiology journal · 2022Article
- Multimodal treatments of brain arteriovenous malformations: a comparison of microsurgical timings after endovascular embolization.Annals of translational medicine · 2022Article
- Maximizing Brain Health After Hemorrhagic Stroke: Bugher Foundation Centers of Excellence.Stroke · 2022Article
- Mutational spectrum of syndromic genes in sporadic brain arteriovenous malformation.Chinese neurosurgical journal · 2022Article
- Childhood stroke.Nature reviews. Disease primers · 2022Review
- Cellular loci involved in the development of brain arteriovenous malformations.Frontiers in human neuroscience · 2022Review
- Review of treatment and therapeutic targets in brain arteriovenous malformation.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Review
- An acquired cerebral arteriovenous malformation after brain abscess treatment: case report and a review of the literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Review
- DELAYED DIAGNOSIS OF AVM PRESENTING WITH STROKE AND SEIZURES IN A YOUNG NIGERIAN: A CASE REPORT.Annals of Ibadan postgraduate medicine · 2021Article
- Central nervous system vascular malformations: A clinical review.Annals of clinical and translational neurology · 2021Review
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Brain arteriovenous malformations (AVMs) are a rare but important cause of intracranial hemorrhage (ICH) in young adults. In this paper, we review both human and animal studies of brain AVM, focusing on the: (1) natural history of AVM hemorrhage, (2) genetic and expression studies of AVM susceptibility and hemorrhage, and (3) strategies for development of a brain AVM model in adult mice. These data target various mechanisms that must act in concert to regulate normal angiogenic response to injury. Based on the various lines of evidence reviewed in this paper, we propose a "response-to-injury" model of brain AVM pathogenesis.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.