Evidence map›Paper›PMID 21725542›Full record

ArticleChemical communications (Cambridge, England)2011

Efficient chemoenzymatic synthesis of sialyl Tn-antigens and derivatives.

Li Ding, Hai Yu, Kam Lau, Yanhong Li, Saddam Muthana, Junru Wang, Xi Chen

Open access · greenAbstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
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  9. Membrane-tethered mucin-like polypeptides sterically inhibit binding and slow fusion kinetics of influenza A virus.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  10. Review
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  12. Synthesis ofFrontiers in immunology · 2019
    Review
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  15. Article
  16. Article
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  19. Glycosyltransferase engineering for carbohydrate synthesis.Biochemical Society transactions · 2016
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Li DingCollege of Science, Northwest A&F University, Yangling, Shaanxi, China.
Hai Yu
Kam Lau
Yanhong Li
Saddam Muthana
Junru Wang
Xi Chen
University of California, Davis · USNorthwest A&F University · CN

Funding

Neu5Gc and anti-Neu5Gc antibodies for detection of cancer and cancer riskU01CA128442 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI VARKI, AJIT P · 2007 to 2011
$2.1M
Studies of Naturally Occurring Structurally Modified CarbohydratesR01GM076360 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHEN, XI · 2006 to 2010
$1.9M
Oligosaccharides as antimicrobials and prebioticsR01HD065122 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHEN, XI · 2010 to 2013
$1.8M
NCI NIH HHS U01 CA128442NCI NIH HHS U01CA128442NICHD NIH HHS R01 HD065122NICHD NIH HHS R01HD065122NIGMS NIH HHS R01 GM076360NIGMS NIH HHS R01GM076360
6 · The paper itself

Abstract

An N-terminal and C-terminal truncated recombinant α2-6-sialyltransferase cloned from Photobacterium sp. JH-ISH-224, Psp2,6ST(15-501)-His(6), was shown to be an efficient catalyst for one-pot three-enzyme synthesis of sialyl Tn (STn) antigens and derivatives containing natural and non-natural sialic acid forms.

Indexed as

Antigens, Tumor-Associated, Carbohydratebeta-D-Galactoside alpha 2-6-SialyltransferaseBiocatalysisHistidineKineticsN-Acylneuraminate CytidylyltransferaseOligopeptidesOxo-Acid-LyasesPhotobacteriumRecombinant ProteinsSialyltransferasesAntigens, Tumor-Associated, Carbohydratebeta-D-Galactoside alpha 2-6-SialyltransferaseHis-His-His-His-His-HisHistidineN-acetylneuraminate lyaseN-Acylneuraminate CytidylyltransferaseOligopeptidesOxo-Acid-LyasesRecombinant Proteinssialosyl-Tn antigenSialyltransferases

Identifiers

PMID21725542
PMCPMC3201767
OpenAlexW1967511968

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.