Trial reportBone marrow transplantation2012
Randomized study of early hospital discharge following autologous blood SCT: medical outcomes and hospital costs.
Trial report in Bone marrow transplantation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- Ambulatory models for autologous stem-cell transplantation: a systematic review of the health impact.Frontiers in immunology · 2024Pooled it
- Pooled it
- Early discharge hospital at home.The Cochrane database of systematic reviews · 2017Pooled it
- Contextual analysis of hematopoietic stem cell transplantation in outpatients.Revista brasileira de enfermagem · 2026Article
- Literature review and expert opinion on the treatment of high-risk acute myeloid leukemia in patients who are eligible for intensive chemotherapy.Frontiers in oncology · 2024Review
- Self-care guidelines for patients in the post-hematopoietic stem cell transplantation period: a scoping review.Revista brasileira de enfermagem · 2023Article
- Article
- Multiple Myeloma Outpatient Transplant Program in the Era of Novel Agents: State-of-the-Art.Frontiers in oncology · 2020Review
- Caregiver availability and patient access to hematopoietic cell transplantation: social worker perspectives inform practice.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019Article
- Protective Isolation for Patients with Haematological Malignancies: A Pilot Study Investigating Patients' Distress and Use of Time.International journal of hematology-oncology and stem cell research · 2017Article
- Outpatient administration of BEAM conditioning prior to autologous stem cell transplantation for lymphoma is safe, feasible, and cost-effective.Cancer medicine · 2016Article
- Italian consensus conference for the outpatient autologous stem cell transplantation management in multiple myeloma.Bone marrow transplantation · 2016Review
- Outpatient care of patients with acute myeloid leukemia: Benefits, barriers, and future considerations.Leukemia research · 2016Review
- Semi-ambulatory autologous peripheral blood SCT in 79 patients with multiple myeloma.Bone marrow transplantation · 2013Article
- Costs and cost-effectiveness of hematopoietic cell transplantation.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2012Review
Corrections and comments
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Authors and funding
14 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report the first randomized study comparing early hospital discharge with standard hospital-based follow-up after high-dose chemotherapy (HDCT) and PBSCT. Patients aged 18-65 years, with an indication of PBSCT for non-leukemic malignant diseases were randomly assigned between two arms. Arm A consisted of early hospital discharge (HDCT during hospitalization, discharge at day 0, home stay with a caregiver, outpatient clinic follow-up). In arm B patients were followed up as inpatients. In total 131 patients were analyzed (66 in arm A and 65 in arm B). Patient characteristics and hematological reconstitution were comparable between the two groups. In arm A, 26 patients were actually discharged early. Patients in group A spent fewer days in hospital (11 vs 12 days, P=0.006). This strategy resulted in a 6% mean cost reduction per patient when compared with the conventional hospital-based group. The early discharge approach within the French health system, while safe and feasible, is highly dependent on social criteria (caregiver availability and home to hospital distance). It is almost always associated with conventional hospital readmission during the aplasia phase, and limits cost savings when considering the whole population of patients benefiting from HDCT in routine clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.