ArticlePhysiological measurement2011
Breath acetone concentration; biological variability and the influence of diet.
Article in Physiological measurement, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05541484 (Ketone Monitoring in T1D), which is not on this map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ketone Monitoring in T1D: Effect of SGLT2i During Usual Care and With Insulin Deficiency
Who cites it
25 citing papers in PubMed, 138 citations in OpenAlex.
- Comprehensive Two-Dimensional Gas Chromatography-Mass Spectrometry Analysis of Exhaled Breath Compounds after Whole Grain Diets.Molecules (Basel, Switzerland) · 2021Trial
- Acetone as biomarker for ketosis buildup capability--a study in healthy individuals under combined high fat and starvation diets.Nutrition journal · 2015Trial
- Exhaled Breath Analysis: From Laboratory Test to Wearable Sensing.IEEE reviews in biomedical engineering · 2025Review
- Elevated blood-ethanol concentration promotes reduction of aliphatic ketones (acetone and ethyl methyl ketone) to secondary alcohols along with slower oxidation to aliphatic diols.Archives of toxicology · 2024Article
- Enhanced detection of low concentration volatile organic compounds using advanced doped zinc oxide sensors.RSC advances · 2023Article
- Online Accurate Detection of Breath Acetone Using Metal Oxide Semiconductor Gas Sensor and Diffusive Gas Separation.Frontiers in bioengineering and biotechnology · 2022Article
- External ears for non-invasive and stable monitoring of volatile organic compounds in human blood.Scientific reports · 2021Article
- Superior Acetone Selectivity in Gas Mixtures by Catalyst-Filtered Chemoresistive Sensors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Article
- COBiosensors · 2020Article
- Microbiota and Malodor-Etiology and Management.International journal of molecular sciences · 2020Review
- Quantification of volatile metabolites in exhaled breath by selected ion flow tube mass spectrometry, SIFT-MS.Clinical mass spectrometry (Del Mar, Calif.) · 2020Review
- Use of Electronic Noses for Diagnosis of Digestive and Respiratory Diseases through the Breath.Biosensors · 2019Review
- Guiding Ketogenic Diet with Breath Acetone Sensors.Sensors (Basel, Switzerland) · 2018Article
- Variation in Exhaled Acetone and Other Ketones in Patients Undergoing Bariatric Surgery: a Prospective Cross-sectional Study.Obesity surgery · 2018Article
- Sniffing Entrapped Humans with Sensor Arrays.Analytical chemistry · 2018Article
- Cinema audiences reproducibly vary the chemical composition of air during films, by broadcasting scene specific emissions on breath.Scientific reports · 2016Article
- A Compendium of Volatile Organic Compounds (VOCs) Released By Human Cell Lines.Current medicinal chemistry · 2016Review
- Measuring breath acetone for monitoring fat loss: Review.Obesity (Silver Spring, Md.) · 2015Review
- Breath volatile organic compounds for the gut-fatty liver axis: promise, peril, and path forward.World journal of gastroenterology · 2014Review
- Breath analysis in disease diagnosis: methodological considerations and applications.Metabolites · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous measurements of acetone concentrations in the exhaled breath of healthy individuals and the small amount of comparable data for individuals suffering from diabetes are briefly reviewed as a prelude to the presentation of new data on the sporadic and wide variations of breath acetone that occur in ostensibly healthy individuals. Data are also presented which show that following a ketogenic diet taken by eight healthy individuals their breath acetone concentrations increased up to five times over the subsequent 6 h. Similarly, the breath acetone increased six and nine times when a low carbohydrate diet was taken by two volunteers and remained high for the several days for which the diet was continued. These new data, together with the previous data, clearly indicate that diet and natural intra-individual biological and diurnal variability result in wide variations in breath acetone concentration. This places an uncertainty in the use of breath acetone alone to monitor blood glucose and glycaemic control, except and unless the individual acts as their own control and is cognizant of the need for dietary control.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.