ArticleJournal of bacteriology2011
The sulfolobicin genes of Sulfolobus acidocaldarius encode novel antimicrobial proteins.
Article in Journal of bacteriology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Article
- Deep learning reveals antibiotics in the archaeal proteome.Nature microbiology · 2025Article
- Extracellular Vesicles in Bacteria, Archaea, and Eukaryotes: Mechanisms of Inter-Kingdom Communication and Clinical Implications.Microorganisms · 2025Review
- Bioactivity of microbial biofilms in extreme environments.Frontiers in microbiology · 2025Review
- Discovery of antibiotics in the archaeome using deep learning.bioRxiv : the preprint server for biology · 2024Article
- Archaeal type six secretion system mediates contact-dependent antagonism.Science advances · 2024Article
- Solid-State Fermentation: Applications and Future Perspectives for Biostimulant and Biopesticides Production.Microorganisms · 2023Review
- Intraspecific antagonism through viral toxin encoded by chronicPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Biogenesis and Biological Functions of Extracellular Vesicles in Cellular and Organismal Communication With Microbes.Frontiers in microbiology · 2022Review
- Archaeal extracellular vesicles are produced in an ESCRT-dependent manner and promote gene transfer and nutrient cycling in extreme environments.The ISME journal · 2021Article
- Extracellular membrane vesicles and nanotubes in Archaea.microLife · 2021Review
- Live Imaging of a Hyperthermophilic Archaeon Reveals Distinct Roles for Two ESCRT-III Homologs in Ensuring a Robust and Symmetric Division.Current biology : CB · 2020Article
- Article
- Extracellular Vesicles-Connecting Kingdoms.International journal of molecular sciences · 2019Review
- Article
- Extracellular membrane vesicles in the three domains of life and beyond.FEMS microbiology reviews · 2019Review
- Extracellular Vesicles and the Promise of Continuous Liquid Biopsies.Journal of pathology and translational medicine · 2018Review
- Review
- Sulfur vesicles from Thermococcales: A possible role in sulfur detoxifying mechanisms.Biochimie · 2015Article
- The identification of a novel Sulfolobus islandicus CAMP-like peptide points to archaeal microorganisms as cell factories for the production of antimicrobial molecules.Microbial cell factories · 2015Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Crenarchaea, such as Sulfolobus acidocaldarius and Sulfolobus tokodaii, produce antimicrobial proteins called sulfolobicins. These antimicrobial proteins inhibit the growth of closely related species. Here we report the identification of the sulfolobicin-encoding genes in S. acidocaldarius. The active sulfolobicin comprises two proteins that are equipped with a classical signal sequence. These proteins are secreted by the cells and found to be membrane vesicle associated. Gene inactivation studies demonstrate that both proteins are required for the bacteriostatic antimicrobial activity. Sulfolobicins constitute a novel class of antimicrobial proteins without detectable homology to any other protein.
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