Evidence map›Paper›PMID 21724934›Full record

ReviewEukaryotic cell2011

RNA interference in fungi: pathways, functions, and applications.

Yunkun Dang, Qiuying Yang, Zhihong Xue, Yi Liu

Open access · diamondAbstract readReview
In one paragraph

Review in Eukaryotic cell, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed, 1 pooled it
17.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

100 citing papers in PubMed, 1 synthesis or guideline pooled it, 232 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Dual RNA-Seq Reveals Molecular Interactions BetweenFoods (Basel, Switzerland) · 2026
    Article
  5. Review
  6. EndophyticJournal of fungi (Basel, Switzerland) · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. The infection of mycovirus down regulatesFrontiers in plant science · 2025
    Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Expanding the Toolbox for Genetic Manipulation inJournal of fungi (Basel, Switzerland) · 2024
    Article

40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yunkun DangDepartment of Physiology, ND13.214A, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9040, USA. Yi.Liu@UTsouthwestern.edu
Qiuying Yang
Zhihong Xue
Yi Liu
The University of Texas Southwestern Medical Center · US

Funding

Mechanism and functions of small RNA pathways in NeurosporaR01GM084283 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI LIU, YI · 2009 to 2015
$2.1M
NIGMS NIH HHS R01 GM084283
6 · The paper itself

Abstract

Small RNA molecules of about 20 to 30 nucleotides function in gene regulation and genomic defense via conserved eukaryotic RNA interference (RNAi)-related pathways. The RNAi machinery consists of three core components: Dicer, Argonaute, and RNA-dependent RNA polymerase. In fungi, the RNAi-related pathways have three major functions: genomic defense, heterochromatin formation, and gene regulation. Studies of Schizosaccharomyces pombe and Neurospora, and other fungi have uncovered surprisingly diverse small RNA biogenesis pathways, suggesting that fungi utilize RNAi-related pathways in various cellular processes to adapt to different environmental conditions. These studies also provided important insights into how RNAi functions in eukaryotic systems in general. In this review, we will discuss our current understanding of the fungal RNAi-related pathways and their functions, with a focus on filamentous fungi. We will also discuss how RNAi can be used as a tool in fungal research.

Indexed as

RNA InterferenceFungiGene Expression RegulationGene SilencingGenomeMicroRNAsModels, GeneticNeurospora crassaRNA-Dependent RNA PolymeraseRNA, FungalRNA, Small InterferingSchizosaccharomycesMicroRNAsRNA-Dependent RNA PolymeraseRNA, FungalRNA, Small Interfering

Identifiers

PMID21724934
PMCPMC3187057
OpenAlexW2024403623

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.