Evidence map›Paper›PMID 21724715›Full record

ArticleThe Journal of rheumatology2011

Patient-reported outcomes in chronic gout: a report from OMERACT 10.

Jasvinder A Singh, Will J Taylor, Lee S Simon, Puja P Khanna, Lisa K Stamp, Fiona M McQueen, Tuhina Neogi, Angelo L Gaffo, Michael A Becker, Patricia A MacDonald and 6 more

Open access · bronzeAbstract readConsensus Statement
In one paragraph

Article in The Journal of rheumatology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 9 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 9 syntheses or guidelines pooled it, 104 citations in OpenAlex.

  1. Colchicine for acute gout.The Cochrane database of systematic reviews · 2021
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Uricosuric medications for chronic gout.The Cochrane database of systematic reviews · 2014
    Pooled it
  5. Allopurinol for chronic gout.The Cochrane database of systematic reviews · 2014
    Pooled it
  6. Pooled it
  7. Lifestyle interventions for acute gout.The Cochrane database of systematic reviews · 2013
    Pooled it
  8. Pooled it
  9. Lifestyle interventions for chronic gout.The Cochrane database of systematic reviews · 2013
    Pooled it
  10. Trial
  11. A Randomized Internet-Based Pilot Feasibility and Planning Study of Cherry Extract and Diet Modification in Gout.Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases · 2020
    Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 11 institutions in 5 countries.

Jasvinder A SinghMedicine Service, Birmingham Veterans Affairs (VA) Medical Center and Division of Rheumatology, Department of Medicine, University of Alabama, Birmingham, AL 35294, USA. jasvinder.md@gmail.com
Will J Taylor
Lee S Simon
Puja P Khanna
Lisa K Stamp
Fiona M McQueen
Tuhina Neogi
Angelo L Gaffo
Michael A Becker
Patricia A MacDonald
Omar Dabbous
Vibeke Strand
Nicola D Dalbeth
Daniel Aletaha
N Lawrence Edwards
H Ralph Schumacher
Takeda (Japan) · JPUniversity of Auckland · NZUniversity of Otago · NZBirmingham VA Medical Center · USCalifornia University of Pennsylvania · USMedical University of Vienna · ATStanford University · USUniversity of Birmingham · GBUniversity of California, Los Angeles · USUniversity of Chicago · USUniversity of Florida · US

Funding

WORK DISABILITY-- PERSONS WITH RHEUMATOID ARTHRITISP60AR047785 · NIAMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI FELSON, DAVID TOBIN · 2001 to 2016
$18.0M
Mayo Clinic Center for Translational Science ActivitiesKL2RR024151 · NCRR · MAYO CLINIC ROCHESTER · PI RIZZA, ROBERT A. · 2006 to 2011
$15.3M
Development and Initial Validation of PROMIS GI Distress ScaleU01AR057936 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KHANNA, DINESH, SPIEGEL, BRENNAN · 2009 to 2013
$2.2M
NCRR NIH HHS 1 KL2 RR024151-01NCRR NIH HHS KL2 RR024151NIAMS NIH HHS AR0557127NIAMS NIH HHS P60 AR047785NIAMS NIH HHS U01 AR057936
6 · The paper itself

Abstract

objectiveTo summarize the endorsement of measures of patient-reported outcome (PRO) domains in chronic gout at the 2010 Outcome Measures in Rheumatology Meeting (OMERACT 10).

methodsDuring the OMERACT 10 gout workshop, validation data were presented for key PRO domains including pain [pain by visual analog scale (VAS)], patient global (patient global VAS), activity limitation [Health Assessment Questionnaire-Disability Index (HAQ-DI)], and a disease-specific measure, the Gout Assessment Questionnaire version 2.0 (GAQ v2.0). Data were presented on all 3 aspects of the OMERACT filters of truth, discrimination, and feasibility. One PRO, health-related quality of life measurement with the Medical Outcomes Study Short-form 36 (SF-36), was previously endorsed at OMERACT 9.

resultsOne measure for each of the 3 PRO of pain, patient global, and activity limitation was endorsed by > 70% of the OMERACT delegates to have appropriate validation data. Specifically, pain measurement by VAS was endorsed by 85%, patient global assessment by VAS by 73%, and activity limitation by HAQ-DI by 71%. GAQ v2.0 received 30% vote and was not endorsed due to several concerns including low internal consistency and lack of familiarity with the measure. More validation studies are needed for this measure.

conclusionWith the endorsement of one measure each for pain, patient global, SF-36, and activity limitation, all 4 PRO for chronic gout have been endorsed. Future validation studies are needed for the disease-specific measure, GAQ v2.0. Validation for PRO for acute gout will be the focus of the next validation exercise for the OMERACT gout group.

Indexed as

Chronic DiseaseDisability EvaluationFeasibility StudiesGoutGout SuppressantsHumansOutcome Assessment, Health CarePain MeasurementReproducibility of ResultsSelf ReportSurveys and QuestionnairesTreatment OutcomeGout Suppressants

Identifiers

PMID21724715
PMCPMC3850171
OpenAlexW2123036861

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.