ArticleBiophysical journal2011
Glycerol-induced membrane stiffening: the role of viscous fluid adlayers.
Article in Biophysical journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 47 citations in OpenAlex.
- Lipid remodeling enables adaptation to chronic hyperosmotic stress.The Journal of cell biology · 2026Article
- Systematic investigation of double emulsion dewetting dynamics for the robust production of giant unilamellar vesicles.Lab on a chip · 2026Article
- A Tridimensional in vitro Epithelial Model of a Simulated Vaginal Environment for the Study ofIntervirology · 2026Article
- Article
- Polyol-Induced 100-Fold Enhancement of Bacterial Ice Nucleation Efficiency.The journal of physical chemistry. C, Nanomaterials and interfaces · 2024Article
- Article
- Fluid preservation in brain banking: a review.Free neuropathology · 2024Article
- Transcriptome Analysis Reveals the Mechanisms of Tolerance to High Concentrations of Calcium Chloride Stress inInternational journal of molecular sciences · 2022Article
- Extrusion: A New Method for Rapid Formulation of High-Yield, Monodisperse Nanobubbles.Small (Weinheim an der Bergstrasse, Germany) · 2022Article
- A Microfluidic Platform for Sequential Assembly and Separation of Synthetic Cell Models.ACS synthetic biology · 2021Article
- Surfactant-free production of biomimetic giant unilamellar vesicles using PDMS-based microfluidics.Communications chemistry · 2021Article
- Carrier Solvents of Electronic Nicotine Delivery Systems Alter Pulmonary Surfactant.Chemical research in toxicology · 2021Article
- Toward Precisely Controllable Acoustic Response of Shell-Stabilized Nanobubbles: High Yield and Narrow Dispersity.ACS nano · 2021Article
- Concurrent visual and acoustic tracking of passive and active delivery of nanobubbles to tumors.Theranostics · 2020Article
- What are the respiratory effects of e-cigarettes?BMJ (Clinical research ed.) · 2019Review
- Contrast enhanced ultrasound imaging by nature-inspired ultrastable echogenic nanobubbles.Nanoscale · 2019Article
- Effects of Copper and pH on the Growth and Physiology ofMetabolites · 2019Article
- BAR scaffolds drive membrane fission by crowding disordered domains.The Journal of cell biology · 2019Article
- Chronic E-Cigarette Exposure Alters the Human Bronchial Epithelial Proteome.American journal of respiratory and critical care medicine · 2018Article
- Tuning endothelial monolayer adhesion: a neutron reflectivity study.American journal of physiology. Lung cellular and molecular physiology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
Lipid interfaces, ranging from cell membranes to thin surfactant layers that stabilize lung alveoli, are integral to living systems. Such interfaces are often subjected to mechanical forces, and because of their membrane-like geometry, they can easily deform by bending into localized folds. In this work, we explore the role of small molecules (i.e., glycerol) on the mechanical stability of model lung surfactant monolayers. We demonstrate that the presence of glycerol increases local monolayer bending stiffness by orders of magnitude. Our x-ray and neutron reflectivity measurements indicate that water is preferentially depleted, or glycerol is preferentially enriched, at the lipid headgroup/solvent interface, and that this glycerol-enriched layer extends O(10Å) beneath the monolayer with an adsorption free energy of -2.5 to -4.6 kJ/mol. The dramatic change in membrane bending stiffness in the presence of the sugar adlayer is understood in terms of two models: 1), lipid antiplasticization by glycerol; and 2), a continuum mechanical model of the viscous adlayer.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.