Evidence map›Paper›PMID 21723049›Full record

Trial reportDrug and alcohol dependence2011

Mindfulness training for smoking cessation: results from a randomized controlled trial.

Judson A Brewer, Sarah Mallik, Theresa A Babuscio, Charla Nich, Hayley E Johnson, Cameron M Deleone, Candace A Minnix-Cotton, Shannon A Byrne, Hedy Kober, Andrea J Weinstein and 2 more

3 registry-linked trialsAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Drug and alcohol dependence, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 174 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
174citing papers in PubMed, 10 pooled it
26.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01144689 nacompletednot on this map

Assessing Mindfulness Training as a Mechanistic Probe for Stress-Induced Brain Activation and Relapse Prevention for Tobacco Addiction

TypeinterventionalSponsorYale UniversityRan2009 to 2013Enrolled42ConditionsCigarette Smoking, Tobacco Smoking, Nicotine Dependence, Smoking CessationArmsMindfulness Training, Smoking Cessation Therapy
NCT02153749 nacompletednot on this mapstarted 2015, after this paper: background citation

Regulation of Craving: Brief Neurocognitive Training and Neural Mechanisms

TypeinterventionalSponsorYale UniversityRan2015 to 2019Enrolled92ConditionsNicotine AddictionArmsCognitive Regulation of Craving, Mindfulness-Based Regulation of Craving
NCT04572126 nacompletednot on this mapstarted 2020, after this paper: background citation

Feasibility and Efficacy of a Brief Mindfulness-Based Smoking Intervention Via the Internet

TypeinterventionalSponsorWayne State UniversityRan2020 to 2021Enrolled80ConditionsSubstance Use, Smoking ReductionArmsMindfulness Intervention, Control Intervention
3 · Its place in the literature

Who cites it

174 citing papers in PubMed, 10 syntheses or guidelines pooled it, 386 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Mindfulness for smoking cessation.The Cochrane database of systematic reviews · 2022
    Pooled it
  4. Pooled it
  5. Guideline
  6. Group behaviour therapy programmes for smoking cessation.The Cochrane database of systematic reviews · 2017
    Pooled it
  7. Food cue reactivity and craving predict eating and weight gain: a meta-analytic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2016
    Pooled it
  8. Pooled it
  9. Pooled it
  10. Smoking cessation interventions for smokers with current or past depression.The Cochrane database of systematic reviews · 2013
    Pooled it
  11. Characteristics of Black Adults Who Never Achieved 24-Hours of Abstinence in a Smoking Cessation Trial: Implications for Improving Treatment Response.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Trial
  12. Trial
  13. Trial
  14. Trial
  15. Randomized trial of mindfulness- and reappraisal-based regulation of craving training among daily cigarette smokers.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2023
    Trial
  16. Trial
  17. Trial
  18. Trial
  19. Mindfulness-based treatment for smoking cessation: a randomized controlled trial.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022
    Trial
  20. Trial

114 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Judson A BrewerDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA. judson.brewer@yale.edu
Sarah Mallik
Theresa A Babuscio
Charla Nich
Hayley E Johnson
Cameron M Deleone
Candace A Minnix-Cotton
Shannon A Byrne
Hedy Kober
Andrea J Weinstein
Kathleen M Carroll
Bruce J Rounsaville
Yale University · US

Funding

TSF to enhance treatment of cocaine dependenceP50DA009241 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M. · 1994 to 2018
$40.5M
SUBSTANCE ABUSEK12DA000167 · NIDA · YALE UNIVERSITY · PI STEPHANIE S O'MALLEY, Marc N Potenza · 1991 to 2026
$17.7M
Interdisciplinary Research on Stress, Self-Control & AddictionUL1DE019586 · NIDCR · YALE UNIVERSITY · PI SINHA, RAJITA · 2008 to 2011
$5.0M
PSYCHOTHERAPY OF SUBSTANCE USE DISORDERSK05DA000457 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M. · 2000 to 2009
$1.2M
DIAGNOSIS &TREATMENT OF SUBSTANCE USE DISORDERSK05DA000089 · NIDA · YALE UNIVERSITY · PI ROUNSAVILLE, BRUCE JAMES · 1988 to 2008
$1.0M
Mindfulness training for smoking cessationR03DA029163 · NIDA · YALE UNIVERSITY · PI BREWER, JUDSON A · 2011 to 2011
$196k
NIDA NIH HHS K05 DA000089NIDA NIH HHS K05 DA000457NIDA NIH HHS K05-DA00089NIDA NIH HHS K05-DA00457NIDA NIH HHS K12 DA000167NIDA NIH HHS K12-DA00167NIDA NIH HHS P50 DA009241NIDA NIH HHS P50-DA09241NIDA NIH HHS R03 DA029163NIDCR NIH HHS UL1 DE019586NIDCR NIH HHS UL 1DE019586-02
6 · The paper itself

Abstract

backgroundCigarette smoking is the leading cause of preventable death in the world, and long-term abstinence rates remain modest. Mindfulness training (MT) has begun to show benefits in a number of psychiatric disorders, including depression, anxiety and more recently, in addictions. However, MT has not been evaluated for smoking cessation through randomized clinical trials.

methods88 treatment-seeking, nicotine-dependent adults who were smoking an average of 20cigarettes/day were randomly assigned to receive MT or the American Lung Association's freedom from smoking (FFS) treatment. Both treatments were delivered twice weekly over 4 weeks (eight sessions total) in a group format. The primary outcomes were expired-air carbon monoxide-confirmed 7-day point prevalence abstinence and number of cigarettes/day at the end of the 4-week treatment and at a follow-up interview at week 17.

results88% of individuals received MT and 84% of individuals received FFS completed treatment. Compared to those randomized to the FFS intervention, individuals who received MT showed a greater rate of reduction in cigarette use during treatment and maintained these gains during follow-up (F=11.11, p=.001). They also exhibited a trend toward greater point prevalence abstinence rate at the end of treatment (36% vs. 15%, p=.063), which was significant at the 17-week follow-up (31% vs. 6%, p=.012).

conclusionsThis initial trial of mindfulness training may confer benefits greater than those associated with current standard treatments for smoking cessation.

Indexed as

NicotineNicotinic AgonistsAdultCarbon MonoxideFemaleFollow-Up StudiesHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedSmokingSmoking CessationTobacco Use DisorderTreatment OutcomeYoung AdultCarbon MonoxideNicotineNicotinic Agonists

Identifiers

PMID21723049
PMCPMC3191261
OpenAlexW2089965180

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.