Evidence map›Paper›PMID 21721921›Full record

ReviewExpert review of neurotherapeutics2011

The interplay between gait, falls and cognition: can cognitive therapy reduce fall risk?

Orit Segev-Jacubovski, Talia Herman, Galit Yogev-Seligmann, Anat Mirelman, Nir Giladi, Jeffrey M Hausdorff

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Expert review of neurotherapeutics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06321263 (Comparison of the Effects of Peripheral Muscle Training and Inspiratory Muscle), which is not on this map. Cited by 126 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
126citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06321263 narecruitingnot on this mapstarted 2024, after this paper: background citation

Comparison of the Effects of Peripheral Muscle Training and Inspiratory Muscle: Randomized Clinical Study.

TypeinterventionalSponsorBiruni UniversityRan2024 to 2025Enrolled30ConditionsMuscle StrengthArmsPeripheral Muscle Training and step aerobics training, Inspiratory Muscle Training and step aerobics training
3 · Its place in the literature

Who cites it

126 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Interventions for preventing falls in people with multiple sclerosis.The Cochrane database of systematic reviews · 2019
    Pooled it
  5. Cognitive-Based Interventions to Improve Mobility: A Systematic Review and Meta-analysis.Journal of the American Medical Directors Association · 2018
    Pooled it
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  12. Baseline health-related quality of life predicts falls: a secondary analysis of a randomized controlled trial.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
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66 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Orit Segev-JacubovskiBeit Rivka Geriatric Rehabilitation Center, Department of Occupational Therapy, Faculty of Social Welfare & Health, University of Haifa, Israel.
Talia Herman
Galit Yogev-Seligmann
Anat Mirelman
Nir Giladi
Jeffrey M Hausdorff

Funding

Gait instability in the elderly with increased fall riskR01AG014100 · NIA · TEL-AVIV SOURASKY MEDICAL CENTER · PI HAUSDORFF, JEFFREY M · 2005 to 2008
$531k
GAIT INSTABILITY IN THE ELDERLY WITH INCREASED FALL RISKR29AG014100 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI HAUSDORFF, JEFFREY M · 1997 to 2001
$238k
NIA NIH HHS AG14100NIA NIH HHS R01 AG014100NIA NIH HHS R29 AG014100
6 · The paper itself

Abstract

In this article, we briefly summarize the incidence and significant consequences of falls among older adults, the insufficient effectiveness of commonly used multifactorial interventions and the evidence linking falls and cognitive function. Recent pharmacologic and nonpharmacologic studies that evaluated the effects of cognitive therapy on fall risk are reviewed. The results of this article illustrate the potential utility of multiple, diverse forms of cognitive therapy for reducing fall risk. The article also indicates that large-scale, randomized controlled trials are warranted and that additional research is needed to better understand the pathophysiologic mechanisms underlying the interplay between human mobility, fall risk and cognitive function. Nonetheless, we suggest that multimodality interventions that combine motor and cognitive therapy should, eventually, be incorporated into clinical practice to enable older adults and patients to move safer and with a reduced fall risk.

Indexed as

Accidental FallsCognition DisordersCognitive Behavioral TherapyGaitHumans

Identifiers

PMID21721921
PMCPMC3163836

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.