Evidence map›Paper›PMID 21721828›Full record

ArticleJournal of biomedical optics2011

Measurement of optical scattering properties with low-coherence enhanced backscattering spectroscopy.

Vladimir Turzhitsky, Andrew J Radosevich, Jeremy D Rogers, Nikhil N Mutyal, Vadim Backman

Open access · bronzeAbstract read
In one paragraph

Article in Journal of biomedical optics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  6. Rectal Optical Markers for In Vivo Risk Stratification of Premalignant Colorectal Lesions.Clinical cancer research : an official journal of the American Association for Cancer Research · 2015
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  15. Polarized Enhanced Backscattering Spectroscopy for Characterization of Biological Tissues at Subdiffusion Length-scales.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society · 2012
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Vladimir TurzhitskyNorthwestern University, Department of Biomedical Engineering, Evanston, Illinois 60208, USA. VT@u.northwestern.edu
Andrew J Radosevich
Jeremy D Rogers
Nikhil N Mutyal
Vadim Backman
Northwestern University · US

Funding

Novel Biophotonics Methodology for Colon Cancer ScreeningR01CA128641 · NCI · NORTHWESTERN UNIVERSITY · PI BACKMAN, VADIM · 2008 to 2012
$7.3M
Mechanisms of Light Scattering in Living TissuesR01EB003682 · NIBIB · NORTHWESTERN UNIVERSITY · PI BACKMAN, VADIM, PRADHAN, PRABHAKAR · 2005 to 2013
$2.2M
NCI NIH HHS R01 CA128641NCI NIH HHS R01CA128641NIBIB NIH HHS R01 EB003682NIBIB NIH HHS R01EB003682
6 · The paper itself

Abstract

Low-coherence enhanced backscattering (LEBS) is a depth selective technique that allows noninvasive characterization of turbid media such as biological tissue. LEBS provides a spectral measurement of the tissue reflectance distribution as a function of distance between incident and reflected ray pairs through the use of partial spatial coherence broadband illumination. We present LEBS as a new depth-selective technique to measure optical properties of tissue in situ. Because LEBS enables measurements of reflectance due to initial scattering events, LEBS is sensitive to the shape of the phase function in addition to the reduced scattering coefficient (μ(s) (*)). We introduce a simulation of LEBS that implements a two parameter phase function based on the Whittle-Matérn refractive index correlation function model. We show that the LEBS enhancement factor (E) primarily depends on μ(s) (*), the normalized spectral dependence of E (S(n)) depends on one of the two parameters of the phase function that also defines the functional type of the refractive index correlation function (m), and the LEBS peak width depends on both the anisotropy factor (g) and m. Three inverse models for calculating these optical properties are described and the calculations are validated with an experimental measurement from a tissue phantom.

Indexed as

Scattering, RadiationAnisotropyFractalsMonte Carlo MethodPhantoms, ImagingReproducibility of ResultsSpectrum Analysis

Identifiers

PMID21721828
PMCPMC3138801
OpenAlexW2153786946

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.