ArticleThe Review of scientific instruments2011
A multiplexed immunoassay system based upon reciprocating centrifugal microfluidics.
Article in The Review of scientific instruments, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Lab on a bead with oscillatory centrifugal microfluidics for fast and complete mixing enables fast and accurate biomedical assays.Scientific reports · 2024Article
- Room temperature roll-to-roll additive manufacturing of polydimethylsiloxane-based centrifugal microfluidic device for on-site isolation of ribonucleic acid from whole blood.Materials today. Bio · 2023Article
- A simple agglutination system for rapid antigen detection from large sample volumes with enhanced sensitivity.Analytica chimica acta · 2023Article
- Integrating Bio-Sensing Array with Blood Plasma Separation on a Centrifugal Platform.Sensors (Basel, Switzerland) · 2023Article
- Capillary Flow-Driven and Magnetically Actuated Multi-Use Wax Valves for Controlled Sealing and Releasing of Fluids on Centrifugal Microfluidic Platforms.Micromachines · 2022Article
- Application of Microfluidics in Immunoassay: Recent Advancements.Journal of healthcare engineering · 2021Review
- Development of Active Centrifugal Pump for Microfluidic CD Platforms.Micromachines · 2020Article
- Utility of Centrifugation-Controlled Convective (C3) Flow for Rapid On-chip ELISA.Scientific reports · 2019Article
- 3D Printing of Elastic Membranes for Fluidic Pumping and Demonstration of Reciprocation Inserts on the Microfluidic Disc.Micromachines · 2019Article
- Hierarchy of human IgG recognition within the Staphylococcus aureus immunome.Scientific reports · 2018Article
- Disk-based enzyme-linked immunosorbent assays using the liquid-aliquoting and siphoning-evacuation technique.Biomicrofluidics · 2018Article
- Network simulation-based optimization of centrifugo-pneumatic blood plasma separation.Biomicrofluidics · 2017Article
- The Effect of Moment of Inertia on the Liquids in Centrifugal Microfluidics.Micromachines · 2016Article
- Challenges in the Use of Compact Disc-Based Centrifugal Microfluidics for Healthcare Diagnostics at the Extreme Point of Care.Micromachines · 2016Review
- A Review of Biomedical Centrifugal Microfluidic Platforms.Micromachines · 2016Review
- CD-Based Microfluidics for Primary Care in Extreme Point-of-Care Settings.Micromachines · 2016Review
- Microsphere integrated microfluidic disk: synergy of two techniques for rapid and ultrasensitive dengue detection.Scientific reports · 2015Article
- Protein Microarrays with Novel Microfluidic Methods: Current Advances.Microarrays (Basel, Switzerland) · 2014Review
- Accelerated immunoassays based on magnetic particle dynamics in a rotating capillary tube with stationary magnetic field.Analytical chemistry · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
A novel, centrifugal disk-based micro-total analysis system (μTAS) for low cost and high throughput semi-automated immunoassay processing was developed. A key innovation in the disposable immunoassay disk design is in a fluidic structure that enables very efficient micro-mixing based on a reciprocating mechanism in which centrifugal acceleration acting upon a liquid element first generates and stores pneumatic energy that is then released by a reduction of the centrifugal acceleration, resulting in a reversal of direction of flow of the liquid. Through an alternating sequence of high and low centrifugal acceleration, the system reciprocates the flow of liquid within the disk to maximize incubation/hybridization efficiency between antibodies and antigen macromolecules during the incubation/hybridization stage of the assay. The described reciprocating mechanism results in a reduction in processing time and reagent consumption by one order of magnitude.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.