ArticleThe Plant cell2011
STENOFOLIA regulates blade outgrowth and leaf vascular patterning in Medicago truncatula and Nicotiana sylvestris.
Article in The Plant cell, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 1 of them a synthesis that pooled it.
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77 citing papers in PubMed, 1 synthesis or guideline pooled it, 157 citations in OpenAlex.
- Overview of molecular mechanisms of plant leaf development: a systematic review.Frontiers in plant science · 2023Pooled it
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- Stem Cell Factors BAM1 and WOX1 Suppressing Longitudinal Cell Division of Margin Cells Evoked by Low-Concentration Auxin in Young Cotyledon of Arabidopsis.International journal of molecular sciences · 2025Article
- WOX1 controls leaf serration development via temporally restricting BRASSINAZOLE RESISTANT 1 and CUP SHAPED COTYLEDON 3 expression in Arabidopsis.Journal of experimental botany · 2025Article
- Transcriptomic and physiological analyses reveal that cytokinin is involved in the compound leaf development of alfalfa.Frontiers in plant science · 2025Article
- A WUSCHEL-related homeobox transcription factor, SlWOX4, negatively regulates drought tolerance in tomato.Plant cell reports · 2024Article
- WOX2 functions redundantly with WOX1 and WOX4 to positively regulate seed germination in Arabidopsis.Planta · 2024Article
- Characterization and expression profiles of WUSCHEL-related homeobox (WOX) gene family in cultivated alfalfa (Medicago sativa L.).BMC plant biology · 2023Article
- The cutting edge of grass leaves.Nature plants · 2023Article
- The developmental dynamics in cool season legumes with focus on chickpea.Plant molecular biology · 2023Review
- Review
- WOX family transcriptional regulators modulate cytokinin homeostasis during leaf blade development in Medicago truncatula and Nicotiana sylvestris.The Plant cell · 2022Article
- Leaf Development inGenes · 2022Review
- Molecular mechanisms underlying leaf development, morphological diversification, and beyond.The Plant cell · 2022Review
- AAoB PLANTS · 2022Article
- Developmental regulation of leaf venation patterns: monocot versus eudicots and the role of auxin.The New phytologist · 2022Review
- CRISPR/Cas9-mediated fine-tuning of miRNA expression in tetraploid potato.Horticulture research · 2022Article
- Genome-wide characterization ofFrontiers in plant science · 2022Article
17 more citing papers are in PubMed but not listed here.
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Authors and funding
13 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dicot leaf primordia initiate at the flanks of the shoot apical meristem and extend laterally by cell division and cell expansion to form the flat lamina, but the molecular mechanism of lamina outgrowth remains unclear. Here, we report the identification of STENOFOLIA (STF), a WUSCHEL-like homeobox transcriptional regulator, in Medicago truncatula, which is required for blade outgrowth and leaf vascular patterning. STF belongs to the MAEWEST clade and its inactivation by the transposable element of Nicotiana tabacum cell type1 (Tnt1) retrotransposon insertion leads to abortion of blade expansion in the mediolateral axis and disruption of vein patterning. We also show that the classical lam1 mutant of Nicotiana sylvestris, which is blocked in lamina formation and stem elongation, is caused by deletion of the STF ortholog. STF is expressed at the adaxial-abaxial boundary layer of leaf primordia and governs organization and outgrowth of lamina, conferring morphogenetic competence. STF does not affect formation of lateral leaflets but is critical to their ability to generate a leaf blade. Our data suggest that STF functions by modulating phytohormone homeostasis and crosstalk directly linked to sugar metabolism, highlighting the importance of coordinating metabolic and developmental signals for leaf elaboration.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.