ArticleScience (New York, N.Y.)2011
Comment on "The mechanism for activation of GTP hydrolysis on the ribosome".
Article in Science (New York, N.Y.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 43 citations in OpenAlex.
- Role of the sarcin-ricin loop of 23S rRNA in biogenesis of the 50S ribosomal subunit.RNA (New York, N.Y.) · 2025Article
- Structural basis of elongation factor 2 switching.Current research in structural biology · 2020Article
- How Ricin Damages the Ribosome.Toxins · 2019Review
- EF-Tu and EF-G are activated by allosteric effects.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Review: Translational GTPases.Biopolymers · 2016Review
- A conserved histidine in switch-II of EF-G moderates release of inorganic phosphate.Scientific reports · 2015Article
- Protein synthesis during cellular quiescence is inhibited by phosphorylation of a translational elongation factor.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Role of a ribosomal RNA phosphate oxygen during the EF-G-triggered GTP hydrolysis.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G.Science advances · 2015Article
- Structural Insights into tRNA Dynamics on the Ribosome.International journal of molecular sciences · 2015Review
- Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2.Nucleic acids research · 2015Article
- A monovalent cation acts as structural and catalytic cofactor in translational GTPases.The EMBO journal · 2014Article
- Ribosome-induced tuning of GTP hydrolysis by a translational GTPase.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Translocation at work.Nature structural & molecular biology · 2013Article
- Structure of EF-G-ribosome complex in a pretranslocation state.Nature structural & molecular biology · 2013Article
- Mechanism of activation of elongation factor Tu by ribosome: catalytic histidine activates GTP by protonation.RNA (New York, N.Y.) · 2013Article
- Modeling catalytic promiscuity in the alkaline phosphatase superfamily.Physical chemistry chemical physics : PCCP · 2013Article
- Elongation factor G bound to the ribosome in an intermediate state of translocation.Science (New York, N.Y.) · 2013Article
- Why nature really chose phosphate.Quarterly reviews of biophysics · 2013Review
- Energetics of activation of GTP hydrolysis on the ribosome.Nature communications · 2013Article
Corrections and comments
- Comment on
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Voorhees et al. (Reports, 5 November 2010, p. 835) determined the structure of elongation factor Tu (EF-Tu) and aminoacyl-transfer RNA bound to the ribosome with a guanosine triphosphate (GTP) analog. However, their identification of histidine-84 of EF-Tu as deprotonating the catalytic water molecule is problematic in relation to their atomic structure; the terminal phosphate of GTP is more likely to be the proper proton acceptor.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.