Evidence map›Paper›PMID 21719117›Full record

ReviewVeterinary immunology and immunopathology2011

Evolutionarily conserved T-cell epitopes on FIV for designing an HIV/AIDS vaccine.

J R Abbott, M P Sanou, J K Coleman, J K Yamamoto

Open access · greenAbstract readReview
In one paragraph

Review in Veterinary immunology and immunopathology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

J R AbbottDepartment of Infectious Diseases and Pathology, College of Veterinary Medicine, University of Florida, P.O. Box 110880, Gainesville, FL 32611, USA.
M P Sanou
J K Coleman
J K Yamamoto
University of Florida · US

Funding

VACCINES FOR FELINE IMMUNODEFICIENCY VIRUSR01AI030904 · NIAID · UNIVERSITY OF FLORIDA · PI YAMAMOTO, JANET K. · 1991 to 2012
$4.2M
HIV/FIV-cat model: a model to identify vaccine epitopesR01AI065276 · NIAID · UNIVERSITY OF FLORIDA · PI YAMAMOTO, JANET K. · 2006 to 2008
$1.1M
NIAID NIH HHS R01 AI030904NIAID NIH HHS R01 AI065276NIAID NIH HHS R01-AI30904NIAID NIH HHS R01-AI65276
6 · The paper itself

Abstract

This review will discuss the current state of the human HIV-1 vaccine trials including the safety consideration of vaccine composition and difficulties in determining and defining protective immunity and epitopes to HIV-1. Vaccines in animal models of lentivirus infection are compared. In particular, the findings from the prototype FIV vaccine and the HIV-1 protein immunizations studies in cats are discussed, as well as the resulting research regarding a potential HIV-1 vaccine design based on evolutionarily conserved T-cell epitopes.

Indexed as

AIDS VaccinesAnimalsCatsClinical Trials as TopicConserved SequenceEpitope MappingEpitopes, T-LymphocyteHIV-1HIV InfectionsHumansImmunodeficiency Virus, FelineVaccines, SyntheticAIDS VaccinesEpitopes, T-LymphocyteVaccines, Synthetic

Identifiers

PMID21719117
PMCPMC4461867
OpenAlexW2061608006

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.