ArticleJournal of medical case reports2011
Severe community-acquired adenovirus pneumonia in an immunocompetent 44-year-old woman: a case report and review of the literature.
Article in Journal of medical case reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Pooled it
- A nomogram for predicting severe adenovirus pneumonia in children.Frontiers in pediatrics · 2023Article
- Clinical and imaging findings of patients diagnosed with adenovirus-positive pneumonia during 2015-2019 in Shanghai, China.Turkish journal of medical sciences · 2022Article
- Uncommon pathogens in an immunocompetent host: respiratory isolation ofBMJ case reports · 2022Article
- Outbreaks of Adenovirus-associated Respiratory Illness on 5 College Campuses in the United States, 2018-2019.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Characteristics of fever and response to antipyretic therapy in military personnel with adenovirus-positive community-acquired pneumonia.Military Medical Research · 2020Article
- Severe community acquired adenovirus pneumonia in an immunocompetent host successfully treated with IV Cidofovir.Respiratory medicine case reports · 2020Article
- Adenovirus Type 7 causing severe lower respiratory tract infection in immunocompetent adults: a comparison of two contrasting cases from an intensive care unit in North West England.Clinical infection in practice · 2019Article
- Perspective on Adenoviruses: Epidemiology, Pathogenicity, and Gene Therapy.Biomedicines · 2019Review
- Clinical features of community acquired adenovirus pneumonia during the 2011 community outbreak in Southern Taiwan: role of host immune response.BMC infectious diseases · 2017Observational
- Severe community-acquired adenovirus pneumonia treated with oral ribavirin: a case report.BMC research notes · 2017Article
- Serology Enhances Molecular Diagnosis of Respiratory Virus Infections Other than Influenza in Children and Adults Hospitalized with Community-Acquired Pneumonia.Journal of clinical microbiology · 2017Article
- Clinical characteristics and factors predicting respiratory failure in adenovirus pneumonia.Respirology (Carlton, Vic.) · 2016Article
- Severe pneumonia caused by adenovirus 7 in pregnant woman: Case report and review of the literature.The journal of obstetrics and gynaecology research · 2016Article
- Severe adenovirus community-acquired pneumonia in immunocompetent adults: chest radiographic and CT findings.Journal of thoracic disease · 2016Article
- Severe Community-Acquired Pneumonia Caused by Human Adenovirus in Immunocompetent Adults: A Multicenter Case Series.PloS one · 2016Article
- Point-of-care testing for respiratory viruses in adults: The current landscape and future potential.The Journal of infection · 2015Review
- Outcomes of early administration of cidofovir in non-immunocompromised patients with severe adenovirus pneumonia.PloS one · 2015Article
- Clinical data analysis of 19 cases of community-acquired adenovirus pneumonia in immunocompetent adults.International journal of clinical and experimental medicine · 2015Article
- [The role of atypical microorganisms and viruses in severe acute community-acquired pneumonia].Reanimation : journal de la Societe de reanimation de langue francaise · 2013Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThis case report describes a rare condition: community-acquired adenovirus pneumonia in an immunocompetent adult. The diagnosis was achieved by using a multiplex real-time reverse transcriptase polymerase chain reaction (RT-PCR) assay and highlights the usefulness of these novel molecular diagnostic techniques in patients hospitalized with acute respiratory illness. We also performed a literature search for previously published cases and present a summary of the clinical, laboratory and radiological features of this condition. CASE PRESENTATION: A 44-year-old immunocompetent Caucasian woman was admitted to our hospital with an acute febrile respiratory illness associated with a rash. Her blood tests were non-specifically abnormal, and tests for bacterial pathogens were negative. Her condition rapidly deteriorated while she was in our hospital and required mechanical ventilation and inotropic support. A multiplex real-time RT-PCR assay performed on respiratory specimens to detect respiratory viruses was negative for influenza but positive for adenovirus DNA. The patient recovered on supportive treatment, and antibiotics were stopped after 5 days.
conclusionsCommunity-acquired adenovirus pneumonia in immunocompetent adult civilians presents as a non-specific acute febrile respiratory illness followed by the abrupt onset of respiratory failure, often requiring mechanical ventilation. Its laboratory and radiological features are typical of viral infections but also are non-specific. Novel multiplex real-time RT-PCR testing for respiratory viruses enabled us to rapidly make the diagnosis in this case. The new technology could be used more widely in patients with acute respiratory illness and has potential utility for rationalization of the use of antibiotics and improving infection control measures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.