ArticleJournal of neurology2012
The clinical and radiological spectrum of posterior reversible encephalopathy syndrome: the retrospective Berlin PRES study.
Article in Journal of neurology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02665598 (Prognostic Observation of Posterior Reversible Encephalopathy Syndrome), which is not on this map. Cited by 87 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prognostic Observation of Posterior Reversible Encephalopathy Syndrome
Who cites it
87 citing papers in PubMed, 5 syntheses or guidelines pooled it, 224 citations in OpenAlex.
- Posterior reversible encephalopathy syndrome associated with antibiotic therapy: a case report and systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Pooled it
- Frequency of ischaemic stroke and intracranial haemorrhage in patients with reversible cerebral vasoconstriction syndrome (RCVS) and posterior reversible encephalopathy syndrome (PRES) - A systematic review.European journal of neurology · 2024Pooled it
- Posterior reversible encephalopathy syndrome (PRES) and infection: a systematic review of the literature.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2019Pooled it
- The multifactorial origin of posterior reversible encephalopathy syndrome in cyclophosphamide-treated lupus patients.Rheumatology international · 2017Pooled it
- Chemotherapy-associated Posterior Reversible Encephalopathy Syndrome: A Case Report and Review of the Literature.The neurologist · 2016Pooled it
- Atypical Posterior Reversible Encephalopathy Syndrome with Intraventricular Hemorrhage in a Patient with Eclampsia : A Case Report.Journal of Korean Neurosurgical Society · 2026Article
- Idiopathic Posterior Reversible Encephalopathy Syndrome (PRES) in a 4-month-old infant: a case report.BMC neurology · 2026Article
- Posterior reversible encephalopathy syndrome as a rare presentation of systemic lupus erythematosus: a case report.Annals of medicine and surgery (2012) · 2026Article
- Posterior reversible encephalopathy syndrome in Colombia a case series.Scientific reports · 2026Article
- Article
- From Gut to Gray Matter: A Case Report of Posterior Reversible Encephalopathy Syndrome in a Pediatric Patient With Celiac Disease.Clinical case reports · 2025Article
- Posterior reversible encephalopathy syndrome (PRES) following cannabis consumption: A rare association.Radiology case reports · 2025Article
- Posterior Reversible Encephalopathy Syndrome Arising from Simultaneous Cranioplasty and Ventriculoperitoneal Shunting: A Case Report.NMC case report journal · 2025Article
- A Pressing Emergency in Oncology: A Case Series of Patients With Posterior Reversible Encephalopathy Syndrome.Cureus · 2024Article
- A 39-year-old woman with transient convulsions and vision disturbances: a case report.Journal of medical case reports · 2024Article
- Article
- Posterior Reversible Encephalopathy Syndrome (PRES) and the Uncommon Sequela: Mesial Temporal Sclerosis.Cureus · 2024Article
- Posterior Reversible Encephalopathy Syndrome in the Immediate Postoperative Period of Gastric Cancer.Cureus · 2023Article
- Can Post-Operative Posterior Reversible Encephalopathy Syndrome (PRES) Be Considered an Insidious Rare Surgical Complication?Brain sciences · 2023Review
- Long-term risk of seizure after posterior reversible encephalopathy syndrome.Annals of clinical and translational neurology · 2023Article
27 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the study was to characterize the clinical and radiological spectrum of posterior reversible encephalopathy syndrome (PRES) in a large cohort. The radiological report data bases of the authors' university hospitals were searched for patients with PRES. Various imaging features at onset of symptoms and on follow-up as well as clinical and paraclinical data were tabulated in those patients fulfilling the criteria for PRES. Exploratory univariate analyses were performed. A total of 96 patients with PRES were included into the study. Wide differences in lesion location, diffusivity, distribution pattern, edema severity, hemorrhage, underlying diseases, symptoms, mean arterial pressure (MAP) and coagulation status were encountered. Hemorrhage occurred significantly more frequently in patients with altered coagulation state and was significantly associated with higher edema grades and with the presence of cytotoxic edema. There was a significant difference in MAP between toxic associations with higher MAP in infection, eclampsy and autoimmune disorders, while lower MAP was found in chemotherapy and immunsupression. In 82% of patients complete or near complete resolution of edema was noted during follow-up. Higher MAP levels were associated with incomplete edema resolution. In 43% of patients residual lesions were seen with a relatively even distribution between focal gliosis, infarction, posthemorrhagic residua, atrophy and laminar necrosis. PRES in this large hospital-based retrospective study comprises a wide radiological and clinical spectrum. Residual lesions were encountered more frequently than commonly expected. Our results point towards a differential contribution of high blood pressure to the course of PRES in different underlying etiologies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.