ReviewImmunologic research2011
Dendritic cells and the maintenance of self-tolerance.
Review in Immunologic research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Immunometabolism in the Tumor Microenvironment: Dual Role in Modulating Anti-Tumor Immunity and Tumor Progression.Asian Pacific journal of cancer prevention : APJCP · 2025Review
- Tolerogenic dendritic cells in type 1 diabetes: no longer a concept.Frontiers in immunology · 2023Review
- Elucidating the Role of Ezh2 in Tolerogenic Function of NOD Bone Marrow-Derived Dendritic Cells Expressing Constitutively Active Stat5b.International journal of molecular sciences · 2020Article
- Exploring the Evidence for an Immunomodulatory Role of Vitamin D in Juvenile and Adult Rheumatic Disease.Frontiers in immunology · 2020Review
- Tolerogenic Dendritic Cells and T-Regulatory Cells at the Clinical Trials Crossroad for the Treatment of Autoimmune Disease; Emphasis on Type 1 Diabetes Therapy.Frontiers in immunology · 2019Review
- Optimal Tolerogenic Dendritic Cells in Type 1 Diabetes (T1D) Therapy: What Can We Learn From Non-obese Diabetic (NOD) Mouse Models?Frontiers in immunology · 2019Review
- Adenovirus-Mediated CCR7 and BTLA Overexpression Enhances Immune Tolerance and Migration in Immature Dendritic Cells.BioMed research international · 2017Article
- Inhibition of Allograft Inflammatory Factor-1 in Dendritic Cells Restrains CD4Frontiers in immunology · 2017Article
- Generation of Tolerogenic Dendritic Cells and Their Therapeutic Applications.Immune network · 2016Review
- Immune tolerance of mice allogenic tooth transplantation induced by immature dendritic cells.International journal of clinical and experimental medicine · 2015Article
- Dendritic cell subsets in type 1 diabetes: friend or foe?Frontiers in immunology · 2013Review
- Immune tolerance induced by intravenous transfer of immature dendritic cells via up-regulating numbers of suppressive IL-10(+) IFN-γ(+)-producing CD4(+) T cells.Immunologic research · 2013Article
- Article
- Activation-induced FoxP3 expression regulates cytokine production in conventional T cells stimulated with autologous dendritic cells.Clinical and vaccine immunology : CVI · 2012Article
- Therapeutic potential of semi-mature dendritic cells for tolerance induction.Frontiers in immunology · 2012Article
- Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Dendritic cells (DC) play important roles in the initiation of immune responses and in the maintenance of self-tolerance. We have been studying the role of DC in the pathogenesis of type 1 diabetes and exploring the ability of specific DC subsets to prevent diabetes in non-obese diabetic (NOD) mice. DC presenting low doses of antigen are capable of inducing and expanding T-regulatory (Treg) cells that have potent suppressive function. We review here our recent findings in this area and highlight the ability of semi-mature therapeutic DC to induce Treg expansion in the absence of exogenous antigen. We discuss how the presentation of endogenous self-antigen by DC may represent a natural mechanism for peripheral self-tolerance that can be harnessed to prevent autoimmunity.
Indexed as
Identifiers
21717078What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.