Evidence map›Paper›PMID 21716938›Full record

ArticleIndian journal of dermatology2011

Cutaneous drug hypersensitivity: immunological and genetic perspective.

Kisalay Ghosh, Gautam Banerjee, Asok Kumar Ghosal, Jayoti Nandi

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of dermatology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Skin on Drugs: Psychotropic Compounds in Cutaneous Biology.International journal of molecular sciences · 2026
    Review
  2. Antiepileptic drug-induced severe cutaneous adverse reactions andTranslational and clinical pharmacology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kisalay GhoshDepartment of Dermatology, MGM Medical College and LSK Hospital, Kishanganj, Bihar, India.
Gautam Banerjee
Asok Kumar Ghosal
Jayoti Nandi
Mahatma Gandhi Memorial Medical College · INInstitute of Post Graduate Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug hypersensitivity is an unpredictable, immunologically mediated adverse reaction, clustered in a genetically predisposed individual. The role of "hapten concept" in immune sensitization has recently been contested by the "pharmacological interaction" hypothesis. After completion of the "human genome project" and with the availability of high-resolution genotyping, genetic susceptibility to hypersensitivity for certain drugs has been proved beyond doubt though the trend is ethnicity and phenotype dependent. Application of this newly acquired knowledge may reduce or abolish the morbidity and mortality associated with cutaneous drug hypersensitivity.

Indexed as

Cutaneous drug hypersensitivitydanger signalethnicityhaptenlinkage disequilibriummajor histocompatibility complexpharmacogenomicspharmacological interaction

Identifiers

PMID21716938
PMCPMC3108509
OpenAlexW2061583741

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.