ArticlePharmacognosy magazine2011
Sterols from the red algae, Gracilaria salicornia and Hypnea flagelliformis, from Persian Gulf.
Article in Pharmacognosy magazine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 31 citations in OpenAlex.
- Anticancer Effects of New Ceramides Isolated from the Red Sea Red AlgaeMarine drugs · 2022Article
- Spinogenesis and Synaptogenesis Effects of the Red SeaweedPreventive nutrition and food science · 2019Article
- Cloning and Functional Characterization of Cycloartenol Synthase from the Red Seaweed Laurencia dendroidea.PloS one · 2016Article
- Article
- Biological activity and chemical constituents of red and brown algae from the persian gulf.Iranian journal of pharmaceutical research : IJPR · 2013Article
- Terpenes From the Root of Salvia hypoleuca Benth.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2012Article
- Alpha-amylase inhibitory activity and sterol composition of the marine algae, Sargassum glaucescens.Pharmacognosy researchArticle
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextTwo of the important algae from Persian Gulf are Gracilaria salicornia and Hypnea flageliformis (Rhodophyta). Antibacterial, antifungal, and cytotoxic effects of the mentioned algae have been presented in the previous studies.
aimIn this study, the isolation and structural elucidation of the sterols from these algae are reported. MATERIALS AND
methodsThe separation and purification of the compounds were carried out with silica gel, sephadex LH(20) column chromatography (CC) and HPLC to obtain six pure compounds 1-6. The structural elucidation of the constituents was based on the data obtained from H-NMR,(13)C-NMR, HMBC, HSQC, DEPT, and EI-MS.
resultsThe isolated compounds from G. salicornia were identified as 22-dehydrocholesterol (1), cholesterol (2), oleic acid (3), and stigmasterol (4), and the isolated constituents from H. flagelliformis were identified as 22-dehydrocholesterol (1), cholesterol (2), oleic acid (3), cholesterol oleate (5), and (22E)-cholesta-5,22-dien-3β-ol-7-one (6) based on the spectral data compared to those reported in the literature.
conclusionRed algae are enriched with cholesterol polysaccharides. We first reported the presence of cholesteryl oleate and (22E)-cholesta-5,22-dien-3β-ol-7-one in H. flagelliformis.
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