ArticleEvidence-based complementary and alternative medicine : eCAM2011
In Vitro and In Vivo Activities of Essential Oil from the Seed of Anethum graveolens L. against Candida spp.
Article in Evidence-based complementary and alternative medicine : eCAM, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 43 citations in OpenAlex.
- The Potential ofPharmaceutics · 2025Article
- Antimicrobial and antioxidant study of combined essential oils of Anethum Sowa Kurz. and Trachyspermum ammi (L.) along with quality determination, comparative histo-anatomical features, GC‒MS and HPTLC chemometrics.Scientific reports · 2024Article
- Effect ofFrontiers in pharmacology · 2024Article
- Antibacterial Activity of a Phenylpropanoid from the Root Extract ofJournal of tropical medicine · 2023Article
- The Effects of Commercially AvailableInfection and drug resistance · 2022Article
- Anti-Inflammation and Protective Effects ofFoods (Basel, Switzerland) · 2021Article
- Use of Essential Oils in Veterinary Medicine to Combat Bacterial and Fungal Infections.Veterinary sciences · 2020Review
- The Confrontation between Ethnopharmacology and Pharmacological Tests of Medicinal Plants Associated with Mental and Neurological Disorders.Evidence-based complementary and alternative medicine : eCAM · 2018Review
- Screening of Fruits of Seven Plants Indicated for Medicinal Use in Iraq.Pharmacognosy magazine · 2017Article
- Liquid crystal precursor mucoadhesive system as a strategy to improve the prophylactic action of Syngonanthus nitens (Bong.) Ruhland against infection by Candida krusei.International journal of nanomedicine · 2015Article
- Antibacterial activity and composition of essential oils from Pelargonium graveolens L'Her and Vitex agnus-castus L.Iranian journal of microbiology · 2012Article
- The mechanism of antifungal action of essential oil from dill (Anethum graveolens L.) on Aspergillus flavus.PloS one · 2012Article
- Antigiardial effect of Anethum graveolens aqueous extract in children.Journal of intercultural ethnopharmacologyArticle
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The essential oil produced from the seed of Anethum graveolens L. (Umbelliferae) was tested in vitro and in vivo anti-Candida activity. The microbroth dilution method was used in the minimal inhibitory concentration (MIC), according to M27-A3 of the guidelines of the Clinical and Laboratory Standard Institute (CLSI). And then, efficacy evaluation of essential oil in the prophylaxis and treatment of experimental vaginal candidiasis was performed in immunosuppressed mice. The anti-Candida activity was analyzed by microbiological and histological techniques and was compared with that of fluconazole (FCZ). The results showed essential oil was active in vitro against all tested strains, with MICs ranging from 0.312 μL/mL (for C. tropicalis, C. parapsilosis, and C. krusei) to 0.625 μL/mL (for 6 isolated C. albicans strains). Essential oil (2% v/v) was highly efficacious in accelerating C. albicans 09-1555 clearance from experimentally infected mice vagina by prophylaxis and therapeutic treatments. In both therapeutic efficacy and prophylaxis studies, the histological findings confirmed the microbiological results. The experimental results revealed that the tested essential oil is effective against vulvovaginal candidiasis in immunosuppressed mice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.