Evidence map›Paper›PMID 21715584›Full record

ArticleJournal of clinical microbiology2011

Molecular characterization of a catalase-negative Staphylococcus aureus subsp. aureus Strain collected from a patient with mitral valve endocarditis and pericarditis revealed a novel nonsense mutation in the katA gene.

Kelvin K W To, Vincent C C Cheng, Jasper F W Chan, Amy C Y Wong, Sandy Chau, Flora H F Tsang, Shirly O T Curreem, Susanna K P Lau, Kwok-Yung Yuen, Patrick C Y Woo

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Rapid differentiation of Staphylococcus aureus subspecies based on MALDI-TOF MS profiles.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2018
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  10. Novel nonsense mutation in the katA gene of a catalase-negative Staphylococcus aureus strain.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Kelvin K W ToCarol Yu Centre for Infection, Research Centre of Infection and Immunology, State Key Laboratory for Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Hong Kong.
Vincent C C Cheng
Jasper F W Chan
Amy C Y Wong
Sandy Chau
Flora H F Tsang
Shirly O T Curreem
Susanna K P Lau
Kwok-Yung Yuen
Patrick C Y Woo
Queen Mary Hospital · CNUniversity of Hong Kong · HKUnited Christian Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of endocarditis and pericarditis caused by catalase-negative Staphylococcus aureus. Molecular characterization revealed a novel nonsense mutation in the katA gene, leading to a loss of 238 amino acids (47% of the wild-type catalase protein), including the heme-binding site, NADPH-binding region, and Tyr-337, essential for catalysis.

Indexed as

AdolescentCatalaseCluster AnalysisCodon, NonsenseDNA, BacterialDNA, RibosomalEndocarditis, BacterialHumansMaleMitral ValveMolecular Sequence DataPericarditisPhylogenyRNA, Ribosomal, 16SSequence Analysis, DNAStaphylococcal InfectionsCatalaseCodon, NonsenseDNA, BacterialDNA, RibosomalRNA, Ribosomal, 16S

Identifiers

PMID21715584
PMCPMC3165592
OpenAlexW2136894005

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.