Evidence map›Paper›PMID 21715578›Full record

ArticleClinical and vaccine immunology : CVI2011

Immunochromatographic test with recombinant Em18 antigen for the follow-up study of alveolar echinococcosis.

Yasuhito Sako, Dennis Tappe, Kenta Fukuda, Yukuharu Kobayashi, Sonoyo Itoh, Matthias Frosch, Beate Grüner, Peter Kern, Akira Ito

Open access · diamondAbstract readEvaluation Study
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Echinococcosis: Advances in the 21st Century.Clinical microbiology reviews · 2019
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Evaluation of immunochromatographic test for the detection of antibodies against Echinococcosis granulosus.Medical science monitor : international medical journal of experimental and clinical research · 2015
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Yasuhito SakoDepartment of Parasitology, Asahikawa Medical University, Midorigaoka Higashi 2-1-1-1, Asahikawa, 078-8510 Hokkaido, Japan. yasusako@asahikawa-med.ac.jp
Dennis Tappe
Kenta Fukuda
Yukuharu Kobayashi
Sonoyo Itoh
Matthias Frosch
Beate Grüner
Peter Kern
Akira Ito
Asahikawa Medical University · JPUniversity Hospital Ulm · DEUniversity of Würzburg · DEAsahikawa Medical College Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The performance of a rapid and simple immunochromatographic test (ICT) with recombinant Em18 (rEm18) antigen for serological follow-up of Echinococcus multilocularis infection was evaluated by comparison with that of an enzyme-linked immunosorbent assay (ELISA) with rEm18, using serum samples from patients who underwent surgery and/or received antiparasitic chemotherapy. The degree of Em18-band intensity on the ICT correlated highly with the absorbance value obtained by the ELISA. The kinetics of antibody levels obtained by the ICT paralleled those of the ELISA. These data suggest that the ICT has high potential as an easy-to-handle, fast, and reliable follow-up tool to monitor the status of alveolar echinococcosis in different stages.

Indexed as

Antigens, HelminthAdolescentAdultAgedAged, 80 and overAnimalsAntibodies, ProtozoanAntiparasitic AgentsClinical Laboratory TechniquesDrug MonitoringEchinococcosisEchinococcosis, HepaticEchinococcus multilocularisFemaleFollow-Up StudiesHumansAntibodies, ProtozoanAntigens, HelminthAntiparasitic AgentsEm18 antigenRecombinant Proteins

Identifiers

PMID21715578
PMCPMC3147335
OpenAlexW2129174740

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.